The aim of this systematic review was to synthesize the existing evidence documenting the psychosocial implications of living with a familial risk of an adult‐onset psychiatric disorder. Six databases were searched systematically to identify qualitative and quantitative studies, which explored perspectives of those at increased risk for psychiatric disorders, as well as the general public. Thematic analysis was used to identify major themes. Thirty‐five articles met the eligibility criteria and reported on the views of 4,896 participants. The literature demonstrates strong interest in psychiatric genetic testing of adults as well as children, whereas attitudes toward prenatal testing were much less positive. Predictors of interest in testing, as well as perceived advantages and disadvantages were identified. Very few studies are available on anticipated and actual reactions to receiving results. Studies show that the majority of participants feel that having a genetic explanation would alleviate some of the stigma associated with mental illness. This review shows that interest in, and predictors of attitudes toward, psychiatric genetic testing are well researched, but the extent to which attitudes will translate into actual testing uptake is unknown. Future research also needs to assess the actual behavioral and psychological impact of genetic testing.

中文翻译：

---

有家族性精神病风险的人的社会心理影响以及对精神病基因检测的态度：对文献的系统评价。

这项系统评价的目的是综合现有证据，证明有成年精神病患者的家族风险的人的社会心理影响。系统地搜索了六个数据库，以进行定性和定量研究，这些研究探讨了精神疾病风险增加的人群以及公众的观点。主题分析用于确定主要主题。符合资格标准的文章有35条，并报告了4,896名参与者的观点。文献表明对成人和儿童的精神病学基因检测有浓厚的兴趣，而对产前检测的态度则不太积极。确定了对测试感兴趣的预测因素以及感知到的优势和劣势。关于接收结果的预期反应和实际反应的研究很少。研究表明，大多数参与者认为进行遗传解释会减轻一些与精神疾病有关的污名。这篇评论表明，人们对精神病基因检测的兴趣和态度预测得到了很好的研究，但是态度在多大程度上转化为实际的检测摄取尚不清楚。未来的研究还需要评估基因测试的实际行为和心理影响。精神病学基因检测已经得到了很好的研究，但是态度在多大程度上转化为实际的检测摄取尚不清楚。未来的研究还需要评估基因测试的实际行为和心理影响。精神病学基因测试已经得到了很好的研究，但是态度在多大程度上转化为实际测试的吸收尚不清楚。未来的研究还需要评估基因测试的实际行为和心理影响。