Porous silicon (PSi) has been established as a promising candidate for a variety of applications in many fields of science and technology. Currently, free-standing PSi is receiving an increasing attention for biomedical applications, such as drug delivery carriers and bio-sensing. In this study, fabrication of free-standing PSi film with attractive structural and optical properties for a prospective biomedical uses, is reported. The film is produced in the dark by a pulsed anodic etching of n⁺- type silicon substrate in an unconventional (HF: HCl: C₂H₅ OH: H₂O₂:H₂O) electrolyte. The macro-porous nature of the produced film is revealed by scanning electron microscopy (SEM) imaging. X-ray diffraction (XRD) and Raman scattering investigations show both amorphous and nano-crystalline phases coexist in the produced film. On ageing it for two months, Fourier transformation infrared (FTIR) spectroscopy results reveal that the produced film exhibits the characteristic of efficiently oxidized PSi with a good stability. In addition to the strong S-band, the room temperature photoluminescence (PL) spectrum of the film exhibits a weaker F-band, which is attributed to the recombination in SiO₂ allocated at surface defects. Moreover, the film adsorption of colchicine drug via immersion process has been investigated by FTIR and UV-spectrophotometric measurements. The results demonstrate that the colchicine is specifically and efficiently adsorbed, with adsorption capacity of around 33%. The results in this study suggest that our fabricated free-standing PSi film can be effectively utilized to prepare PSi nanoparticles for forthcoming drug delivery applications.

多孔硅（PSi）已被确定为在许多科学和技术领域中的各种应用的有前途的候选者。当前，独立式PSi在生物医学应用（例如药物输送载体和生物传感）中越来越受到关注。在这项研究中，报道了具有吸引力的结构和光学特性的独立式PSi膜的制造，可用于预期的生物医学用途。通过在非常规的（HF：HCl：C ₂ H ₅ OH：H ₂ O ₂：H _2）中对n ⁺型硅衬底进行脉冲阳极蚀刻，在黑暗中产生薄膜。O）电解质。通过扫描电子显微镜（SEM）成像揭示了产生的膜的大孔性质。X射线衍射（XRD）和拉曼散射研究表明，非晶相和纳米晶相共存于生产的薄膜中。老化两个月后，傅立叶变换红外（FTIR）光谱结果表明，所制得的薄膜具有有效氧化的PSi的特性，并且具有良好的稳定性。除了强S波段外，薄膜的室温光致发光（PL）光谱还具有较弱的F波段，这归因于SiO _2中的重组分配在表面缺陷处。此外，已经通过傅立叶变换红外光谱和紫外分光光度法研究了秋水仙碱药物通过浸没过程的膜吸附。结果表明秋水仙碱被特异性和有效地吸附，吸附能力约为33％。这项研究的结果表明，我们制造的独立式PSi膜可以有效地用于制备PSi纳米颗粒，以用于即将到来的药物递送应用。