A STIMulating journey into optogenetic engineering.,Cell Calcium

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A STIMulating journey into optogenetic engineering.
Cell Calcium ( IF 4.3 ) Pub Date : 2020-05-04 , DOI: 10.1016/j.ceca.2020.102197
Guolin Ma ₁ , Yubin Zhou ₁

Affiliation

Genetically-encoded calcium actuators (GECAs) stemmed from STIM1 have enabled optical activation of endogenous ORAI1 channels in both excitable and non-excitable tissues. These GECAs offer new non-invasive means to probe the structure-function relations of calcium channels and wirelessly control the behavior of awake mice.

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