Microcellular scaffolds were prepared using high pressure fluids. Solutions of biodegradable material Poly (lactic-co-glycolic) acid (PLGA) in a green solvent such as ethyl lactate was used as the scaffold matrix. To carry out polymer foaming from polymer solutions allows the possibility of reducing the working temperature. The effect of the ratio lactide to glycolide of the polymer, the working pressure, the initial concentration of the polymer in the solvent and the depressurization time were the variables studied at a temperature of 25 °C. The morphology of the foams obtained was characterized based on the cell diameter and its standard deviation, indicator of the homogeneity of the scaffolds obtained, as well as the density of cells. In addition, a study was performed on how the glass transition temperature (Tg) of a polymer is modified by the plasticizing effect of CO₂ pressure.

使用高压流体制备微细胞支架。可生物降解材料聚（乳酸-乙醇酸）酸（PLGA）在绿色溶剂（如乳酸乙酯）中的溶液用作支架基质。从聚合物溶液中进行聚合物发泡可以降低工作温度。聚合物中丙交酯与乙交酯的比率，工作压力，聚合物在溶剂中的初始浓度和降压时间的影响是在25°C温度下研究的变量。基于孔直径及其标准偏差，所获得的支架的均质性指标以及孔密度来表征所获得的泡沫的形态。此外，₂压力。