SummaryThe objective of this study was to compare the rates of clinical pregnancy after the transfer of vitrified and thawed human embryos on days 3, 4 and 5 of embryonic development. In this retrospective study, the results of 148 embryo transfer cycles, using embryos frozen and thawed over the 3-year period between January 2016 and December 2018 at the Gülhane Training and Research Hospital Department of Gynecology and Obsterics Reproductive Medical Center of the University of Health Sciences, Ankara, Turkey were examined. Following embryo transfer – including 29 dissolved embryos frozen on day 3, 80 frozen on day 4, and 39 frozen on day 5 – results were examined in terms of clinical pregnancy rates. In this study, across all three groups, no significant differences were observed in terms of patient age, the number of oocytes collected, infertility reasons, the number of embryos dissolved, transfer day, or the number of embryos transferred. According to the transfer day, the rates of clinical pregnancy and ongoing pregnancy were significantly higher for embryos frozen on day 4 and transferred on day 5. Significantly higher rates of pregnancy and live birth were determined during in vitro fertilization (IVF) treatment with the freezing of human embryos on day 4 and the transfer of those embryos on day 5.

中文翻译：

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卵裂期、桑椹胚期和胚泡期玻璃化解冻的人类胚胎移植结果调查

摘要本研究的目的是比较在胚胎发育第 3、4 和 5 天移植玻璃化和解冻的人类胚胎后的临床妊娠率。在这项回顾性研究中，148 个胚胎移植周期的结果，使用了 2016 年 1 月至 2018 年 12 月期间在 Gülhane 培训与研究医院妇产科生殖医学中心的 3 年期间冷冻和解冻的胚胎科学，安卡拉，土耳其进行了检查。胚胎移植后（包括第 3 天冷冻的 29 个溶解胚胎、第 4 天冷冻的 80 个和第 5 天冷冻的 39 个胚胎）根据临床妊娠率检查结果。在这项研究中，在所有三组中，在患者年龄、收集的卵母细胞数量、不孕的原因，胚胎溶解的数量，移植天数，或移植的胚胎数量。根据移植日，第 4 天冷冻胚胎和第 5 天移植胚胎的临床妊娠率和持续妊娠率显着较高。体外受精 (IVF) 治疗，第 4 天冷冻人类胚胎，第 5 天移植这些胚胎。