Today, due to the growth of industries and spread of the use of various instruments and devices that produce high noise levels, it is necessary to pay more attention to the effects of exposure to noise on organs and tissues in the body. The importance of the immune system in fighting external and pathogenic factors has raised the need to consider external factors (such as harmful physical factors) and make efforts to avoid producing them. In this systematic review, 811 potentially relevant studies were found in Google Scholar, PubMed, and Web of Science databases, of which 32 different English-written articles were included in the study. The method of searching and systematically reviewing articles was based on the assessment tool of the multiple systematic reviews (AMSTAR) method. The results of this study suggested that noise could affect the function of the immune system and its components by affecting other systems and organs of the body, including the central nervous system, auditory system, circulatory system, and endocrine gland. Moreover, it can be hypothesized that noise affects immune system by producing the NADPH oxidase (Nox) and reactive oxygen species (ROS).

中文翻译：

---

噪声暴露引起的炎症和免疫学变化：系统评价。

今天，由于工业的发展和各种产生高噪音水平的仪器和设备的使用的普及，有必要更加关注接触噪音对人体器官和组织的影响。免疫系统在对抗外部和致病因素方面的重要性提出了考虑外部因素（如有害的物理因素）并努力避免产生这些因素的必要性。在本系统评价中，在 Google Scholar、PubMed 和 Web of Science 数据库中发现了 811 项可能相关的研究，其中包括 32 篇不同的英文文章。检索和系统评价文章的方法基于多重系统评价（AMSTAR）方法的评估工具。这项研究的结果表明，噪音可以通过影响身体的其他系统和器官，包括中枢神经系统、听觉系统、循环系统和内分泌腺来影响免疫系统及其组成部分的功能。此外，可以假设噪声通过产生 NADPH 氧化酶 (Nox) 和活性氧 (ROS) 来影响免疫系统。