A new study shows how myeloid-derived suppressor cells paralyse CD8+ T cell effector functions by transferring the metabolite methylglyoxal directly into the T cell cytosol, where it depletes essential amino acids.

中文翻译：

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MDSC代谢物使T细胞昏迷。

一项新的研究表明，髓样来源的抑制细胞如何通过将代谢产物甲基乙二醛直接转移到T细胞胞质溶胶中来使CD8 + T细胞效应子瘫痪，并在其中消耗必需氨基酸。