Pulmonary disease is known to cause remodeling of tissue structure, resulting in altered viscoelastic properties; yet the foundation for understanding this phenomenon is still nascent and will enable scientific insights regarding lung functionality. In order to characterize the viscoelastic response of pulmonary airways, uniaxial tensile experiments are conducted on porcine extra- and intra-parenchymal bronchial regions, measuring both axially and circumferentially oriented tissue. Anisotropic and heterogeneous effects on preconditioning and hysteresis are substantial, linking to energy dissipation expectancies. Stress relaxation is rheologically modeled using several classical configurations of discrete spring and dashpot elements; among them, Standard Linear Solid (SLS) and Maxwell-Weichart exhibit better fit performance. Enhanced fractional order derivative SLS (FSLS) model is also evaluated through use of a hybrid spring-pot of order α. FSLS outperforms the conventional models, demonstrating superior representation of the stress-relaxation curve's initial value and non-linear asymptotic decent. FSLS parameters exhibit notable orientation- and region-specific values, trending with observed tissue structural constituents, such as glycosaminoglycan and collagen. To the best of our knowledge, this work is the first to characterize proximal and distal bronchial energy efficiency and contextualize tissue biochemical composition in view of experimental measures and viscoelastic trends. Results provide a foundation for future investigations, particularly for understanding the role of viscoelasticity in diseased states.

众所周知，肺部疾病会导致组织结构的重塑，从而导致粘弹性变。然而，了解这种现象的基础仍是新生的，并将使有关肺功能的科学见解成为可能。为了表征肺气道的粘弹性响应，在猪的实质外和实质内支气管区域进行了单轴拉伸实验，测量了轴向和周向组织。各向异性和异质性对预处理和磁滞的影响很大，这与预期的能量耗散有关。应力松弛是使用离散弹簧和阻尼元件的几种经典配置进行流变建模的。其中，标准线性实体（SLS）和Maxwell-Weichart具有更好的拟合性能。α。FSLS优于传统模型，证明了应力松弛曲线的初始值和非线性渐近体面的出色表现。FSLS参数显示出显着的取向和区域特异性值，并随观察到的组织结构成分（如糖胺聚糖和胶原蛋白）而变化。据我们所知，这项工作是第一个表征近端和远端支气管能量效率并根据实验手段和粘弹性趋势对组织生化成分进行背景分析的研究。结果为将来的研究奠定了基础，尤其是为了解粘弹性在患病状态中的作用提供了基础。