Like social networks, neurons in the brain are organized in neuronal ensembles that constrain and at the same time enrich the role and temporal precision of activity of individual neurons. Changes in coordinated firing across cortical neurons as well as selective changes in timing and sequential order across neurons that are important for encoding of novel information have collectively been known as ensemble temporal coding. Here we review recent findings on the role of online and offline temporal coding within sequential cell assemblies from the rodent hippocampus thought be important for memory encoding and consolidation and for spatial navigation. We propose that temporal coding in the rodent hippocampus represented as plasticity in replay activity relies primarily on subtle and selective changes in coordinated firing within the microstructure of individual cell assembly organization during sleep.

中文翻译：

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海马体中的细胞组装、序列和时间编码。

像社交网络一样，大脑中的神经元被组织成神经元集合，这些集合限制并同时丰富了单个神经元活动的作用和时间精度。跨皮层神经元协调放电的变化以及跨神经元的时间和顺序顺序的选择性变化，这些对新信息的编码很重要，统称为集成时间编码。在这里，我们回顾了最近关于在线和离线时间编码在啮齿动物海马序列细胞集合中的作用的研究结果，认为这对记忆编码和整合以及空间导航很重要。