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Feline sporotrichosis in Asia
Brazilian Journal of Microbiology ( IF 2.1 ) Pub Date : 2020-05-03 , DOI: 10.1007/s42770-020-00274-5
Hock Siew Han 1 , Rui Kano 2
Affiliation  

Sporothrix schenckii sensu lato is currently recognized as a species complex with only Sporothrix brasiliensis , Sporothrix schenckii sensu stricto, Sporothrix globosa and Sporothrix pallida identified to cause disease in the cat. Feline sporotrichosis in Asia is mainly reported from Malaysia where a single clonal strain of clinical clade D, Sporothrix schenckii sensu stricto manifesting low susceptibility to major antifungal classes, has been identified as the agent of the disease. Sporothrix globosa has been identified to cause disease from a single cat in Japan while the specific species of agent has not been identified yet for the disease in Thailand. Despite efforts to elucidate and describe the pathogenicity of the agent and the disease it causes, the paucity of data highlights the need for further molecular epidemiological studies to characterize this fungus and the disease it causes in Asia. Its prognosis remains guarded to poor due to issues pertaining to cost, protracted treatment course, zoonotic potential and low susceptibility of some strains to antifungals.

中文翻译:

亚洲猫孢子丝菌病

申克孢子丝菌目前被认为是一个物种复合体,只有巴西孢子丝菌、申克孢子丝菌、严格申克孢子丝菌、球形孢子丝菌和苍白孢子丝菌被确定会引起猫的疾病。亚洲猫孢子丝菌病主要由马来西亚报道,其中临床分支 D 的单一克隆菌株申克孢子丝菌 (Sporothrix schenckii sensu stricto) 对主要抗真菌药物的敏感性较低,已被确定为该疾病的病原体。在日本,球形孢子丝菌已被确定可引起一只猫的疾病,而在泰国,尚未确定导致该疾病的具体病原体种类。尽管人们努力阐明和描述该病原体的致病性及其引起的疾病,但数据的缺乏凸显了需要进一步的分子流行病学研究来描述这种真菌及其在亚洲引起的疾病的特征。由于成本、疗程长、人畜共患潜力以及某些菌株对抗真菌药物敏感性低等问题,其预后仍然较差。
更新日期:2020-05-03
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