Interplane bulk motion analysis and removal based on normalized cross-correlation in optical coherence tomography angiography.,Journal of Biophotonics

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Interplane bulk motion analysis and removal based on normalized cross-correlation in optical coherence tomography angiography.
Journal of Biophotonics ( IF 2.0 ) Pub Date : 2020-05-13 , DOI: 10.1002/jbio.202000046
Jinyu Fan _{1,

2} , Yi He ₂ , Pinghe Wang ₃ , Guangxing Liu ₂ , Guohua Shi _{1,

2,

3,

4}

Affiliation

Bulk motion seriously degrades the image quality of optical coherence tomography angiography (OCTA). Conventional correction methods focus on in‐plane displacement, while the bulk motion component perpendicular to B‐scans also introduces noise. This work first presents an evaluation of this component using a specific scan protocol and an approximate expression derived from peak‐normalized cross‐correlation values, and then quantitatively assesses how interplane bulk motion noise reduce the sensitivity of cross‐sectional angiograms. Finally, we developed a repetitive bulk motion correction method based on the estimated displacements and redundant volume scans. The correction does not require registration and angiogram reconstruction of low flow sensitivity frames, and the results of in vivo mice skin OCTA imaging experiments show that the proposed method can effectively reduce bulk motion noise caused by cardiac and respiratory motion and occasional shaking, and improve OCTA image quality, which has practical significance for clinical OCTA diagnosis and analysis.

中文翻译：

基于光学相干断层扫描血管造影中归一化互相关的平面间整体运动分析和去除。

整体运动会严重降低光学相干断层扫描血管造影（OCTA）的图像质量。常规校正方法着重于平面内位移，而垂直于B扫描的整体运动分量也会引入噪声。这项工作首先使用特定的扫描协议和从峰归一化互相关值得出的近似表达式，对该组件进行评估，然后定量评估平面内整体运动噪声如何降低横截面血管造影的敏感性。最后，我们根据估算的位移和多余的体积扫描结果开发了一种重复的批量运动校正方法。该校正不需要对低流量敏感度框架进行配准和血管造影重建，

更新日期：2020-05-13

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