Antimicrobial resistance has been declared by the World Health Organization as one of the biggest threats to public health and Acinetobacter baumannii is a notable example. A. baumannii is an important human nosocomial pathogen, being along with other multidrug resistant (MDR) bacteria, one of the biggest public health concerns worldwide. In Veterinary Medicine, resistance patterns of Acinetobacter species other than A. baumanii are unclear, and the scarce information available is limited and fragmented. We applied a statistical modeling approach to investigate the occurrence, clinical relevance and antimicrobial resistant phenotypes of Acinetobacter spp. originated from animals. Seven Acinetobacter species were identified in clinical specimens of more than 15 different domestic, zoo and exotic animal species. We found a high rate of MDR A. baumannii of canine origin with some of these isolates originating from serious systemic or wound infections, which highlights their potential pathogenic profile and spread in the human environment. Data also revealed different antimicrobial resistance patterns of animal-origin Acinetobacter species, emphasizing the necessity to implement specific antimicrobial susceptibility recommendations for animal isolates as there are no such clinical breakpoints currently in place. This study provides substantial advancing in our understanding of Acinetobacter spp. in animal clinical specimens, and highlights the role of animals in the dynamics of multidrug resistance in bacteria. The data presented here is a valuable source of information for further establishment of clinical breakpoints for susceptibility testing of animal-associated Acinetobacter isolates.

世界卫生组织已宣布抗生素耐药性是对公众健康的最大威胁之一，鲍曼不动杆菌就是一个显着的例子。鲍曼不动杆菌是一种重要的人类院内病原体，与其他多重耐药 (MDR) 细菌一样，是全球最大的公共卫生问题之一。在兽医学中，鲍曼不动杆菌以外的不动杆菌属的耐药模式尚不清楚，可用的稀缺信息有限且零散。我们应用统计建模方法来研究不动杆菌属的发生率、临床相关性和抗菌素耐药表型。起源于动物。七在超过 15 种不同的家养、动物园和外来动物物种的临床标本中鉴定出不动杆菌属。我们发现犬源鲍曼不动杆菌的耐多药率很高，其中一些分离株源自严重的全身或伤口感染，这突出了它们潜在的致病特征并在人类环境中传播。数据还揭示了动物源不动杆菌属的不同抗菌素耐药模式，强调有必要对动物分离株实施特定的抗菌素敏感性建议，因为目前没有这样的临床断点。这项研究为我们对不动杆菌的理解提供了实质性的进展属 在动物临床标本中，并强调了动物在细菌多药耐药动态中的作用。此处提供的数据是进一步建立动物相关不动杆菌分离株药敏试验临床断点的宝贵信息来源。