Effects of exercise frequency on the gut microbiota in elderly individuals.,MicrobiologyOpen

当前位置： X-MOL 学术 › Microbiologyopen › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Effects of exercise frequency on the gut microbiota in elderly individuals.
MicrobiologyOpen ( IF 3.9 ) Pub Date : 2020-05-01 , DOI: 10.1002/mbo3.1053
Qiwei Zhu ₁ , Shangfei Jiang ₂ , Guankui Du ₁

Affiliation

Growing evidence has shown that exercise can affect the gut microbiota. The effects of exercise frequency on the gut microbiota in elderly individuals are still largely unknown. In the present study, samples from 897 elderly and 1,589 adult individuals (18–60 years old) from the American Gut Project were screened. Microbial diversity and composition were analyzed by QIIME2, and microbial function was predicted by PICRUSt2. The outcomes were further analyzed by STAMP. The analysis showed that the α‐diversity of gut microbiota increased with increasing age, and regular exercise reshaped the alterations in microbial composition and function induced by aging. Moreover, the α‐diversity of gut microbiota was higher in overweight elderly individuals than in normoweight elderly individuals, and regular exercise significantly affected the microbial composition and function in overweight elderly individuals. In conclusion, we revealed that regular exercise benefits elderly individuals, especially overweight elderly individuals, by modulating the gut microbiota.

中文翻译：

运动频率对老年人肠道菌群的影响。

越来越多的证据表明，运动会影响肠道菌群。运动频率对老年人肠道菌群的影响仍然未知。在本研究中，对来自美国肠道项目的897名老年人和1589名成年人（18-60岁）的样本进行了筛选。用QIIME2分析微生物的多样性和组成，用PICRUSt2预测微生物的功能。结果通过STAMP进一步分析。分析表明，肠道菌群的α多样性随年龄的增长而增加，规律的运动重塑了衰老引起的微生物组成和功能的改变。此外，超重老年人的肠道菌群的α多样性高于正常体重老年人，经常运动会严重影响超重老年人的微生物组成和功能。总之，我们发现，经常锻炼可以通过调节肠道菌群使老年人，特别是超重老年人受益。

更新日期：2020-05-01

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11