Organic materials, such as conjugated polymers, are attractive building blocks for bioelectronic interfaces. In particular, organic semiconductors show excellent performance in light-mediated excitation and silencing of neuronal cells and tissues. However, the main challenges of these organic photovoltaic interfaces compared to inorganic prostheses are the limited adhesion of conjugated polymers in aqueous environments and the exploitation of materials responsive in the visible spectrum. Here, we show a photovoltaic organic interface optimized for neuronal stimulation in the near-infrared spectrum. We adjusted the organic materials by chemical modification in order to improve the adhesion in an aqueous environment and to modulate the photoelectrical stimulation efficiency. As proof-of-principle, we tested this interface on explanted degenerated mice retinas, thus providing results on the efficiency and reliability of the device as an implant for neural stimulation.

有机材料（例如共轭聚合物）是生物电子界面的有吸引力的构建基块。特别地，有机半导体在神经元细胞和组织的光介导的激发和沉默中表现出优异的性能。然而，与无机假体相比，这些有机光伏界面的主要挑战是共轭聚合物在水性环境中的粘合力有限以及对可见光谱响应材料的开发。在这里，我们显示了为近红外光谱中的神经元刺激优化的光伏有机界面。我们通过化学改性来调节有机材料，以提高在水性环境中的附着力并调节光电刺激效率。作为原理证明，