Heavy Elements Revealed in Jejunum of Simian Immunodeficiency Virus Infected Monkeys by Microparticle Induced X‐Ray Emission,Physica Status Solidi (A) - Applications and Materials Science

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Heavy Elements Revealed in Jejunum of Simian Immunodeficiency Virus Infected Monkeys by Microparticle Induced X‐Ray Emission
Physica Status Solidi (A) - Applications and Materials Science Pub Date : 2020-04-25 , DOI: 10.1002/pssa.202000107
Harry J. Whitlow _{1,

2} , Naresh T. Deoli _{1,

2} , Armin de Vera ₁ , Karen Morgan ₃ , Francois Villinger _{3,

4}

Affiliation

Archived jejunum tissue block specimens from control and simian immunodeficiency virus‐infected rhesus macaques are characterized using particle‐induced X‐ray emission (PIXE) in a MeV ion microprobe with 2 MeV protons. The results show considerable variance in the concentration of some elements (Ti, Mn, and Fe) between viremic and control tissue. Ti, Mn, and Fe are present at levels 50‐fold lower in samples from viremic versus control monkeys, a difference markedly higher than previously reported for infections. Pb and Ti are observed particularly in the crypts of both viremic and control jejunum samples. This is likely to be caused by ingestion of paint fragments picked from the cages used to house the animals.

中文翻译：

微粒诱导的X射线发射显示猿猴免疫缺陷病毒空肠感染重金属元素

来自对照和猿猴免疫缺陷病毒感染的恒河猴的空肠组织阻断标本的特征是在具有2个MeV质子的MeV离子微探针中使用粒子诱导X射线发射（PIXE）进行表征。结果显示病毒血症组织和对照组织之间某些元素（Ti，Mn和Fe）的浓度存在很大差异。病毒性猴和对照猴的样品中钛，锰和铁的含量低50倍，差异明显高于先前报道的感染。Pb和Ti特别是在病毒性空肠和对照空肠样品的隐窝中观察到。这很可能是由于摄取了从用于饲养动物的笼子中拾取的油漆碎片引起的。

更新日期：2020-04-25

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