To investigate the ovarian and uterine blood flow responses, hemodynamic, circulating ovarian hormones and nitric oxide (NO) after end of treatment by Folltropin. Holstein Friesian (12) cows previously synchronized with CIDR underwent Doppler ultrasound after administrating of FSH daily for 4 days in eight injections started on day 10 of the second ovulation (day −5). Oestradiol (E2), progesterone (P4) and nitric oxide (NOMs) were measured. During the follicular phase, follicle area and antrum area of the second cycle reached maximum value on the day of ovulation compared with that in the first cycle, while during the luteal phase, both showed a pattern of increase and decrease. The luteal area and total coloured area increased till day 10 in the first and second cycle. The first cycle ipsilateral ovarian artery (Ov.A) had higher pulsatility (PI) (p  = .001), resistance (RI) (p  = .001), peak velocity (PSV) (p  = .009) and lower end‐diastolic velocity (EDV) (p  = .003) compared with the second cycle. The increased ipsilateral Ov.A PSV (p  = .009) was accompanied by lower EDV. The first cycle ipsilateral middle uterine artery (MUA) had higher PI (p  = .001) and RI (p  = .001), with lower PSV (p  = .001) and EDV (p  = .001). It was concluded that blood flow of ovarian and middle uterine arteries changed after the end of superstimulation as the increased ipsilateral Ov. A and MUA PSVs accompanied by lower EDV and both Doppler indices that reflect the amount of ovarian and uterine blood flow waveform.

中文翻译：

---

母牛过度刺激后的前两个周期，卵巢和子宫动脉的血流波形响应。

在Foltropin治疗结束后，研究卵巢和子宫的血流反应，血液动力学，循环性卵巢激素和一氧化氮（NO）。在第二次排卵的第10天（第-5天）开始的八次注射中，每天施用FSH 4天后，先前与CIDR同步的Holstein Friesian（12）母牛接受了多普勒超声检查。测量了雌二醇（E2），孕酮（P4）和一氧化氮（NOM）。在卵泡期，与第一周期相比，第二周期的卵泡面积和胃窦面积在排卵日达到最大值，而在黄体期，卵泡面积和胃窦面积均呈增加和减少的趋势。在第一个和第二个周期的第10天，黄体面积和总有色面积增加。第一周期同侧卵巢动脉（Ov.A）的搏动性（PI）较高（p  = .001），阻力（RI）（p  = .001），峰值速度（PSV）（p  = .009）和较低的舒张末期速度（EDV）（p  = .003）。同侧Ov.A PSV升高（p  = .009 ）并伴有EDV降低。第一周期同侧子宫中动脉（MUA）的PI（p  = .001）和RI（p  = .001）较高，而PSV（p  = .001）和EDV（p = .001）。结论是，在超刺激结束后，随着同侧Ov的增加，卵巢和子宫中动脉的血流发生了变化。A和MUA PSV伴有较低的EDV和反映卵巢和子宫血流波形量的多普勒指数。