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Imaging features in patients with SAPHO/CRMO: a pictorial review.
Japanese Journal of Radiology ( IF 2.9 ) Pub Date : 2020-04-30 , DOI: 10.1007/s11604-020-00953-1
Hidetomo Himuro 1 , Seiji Kurata 1 , Shuji Nagata 1 , Akiko Sumi 1 , Fumihiro Tsubaki 1 , Akihiro Matsuda 1 , Kiminori Fujimoto 1 , Toshi Abe 1
Affiliation  

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome and chronic recurrent multifocal osteomyelitis (CRMO) have been described as disorders of chronic osteoarthritic inflammation frequently associated with skin manifestations, and SAPHO and CRMO (SAPHO/CRMO) are rare autoinflammatory disorders of unknown etiology. SAPHO tends to occur in adults and CRMO predominantly occurs in children and adolescents. SAPHO/CRMO can affect any skeletal region (e.g., anterior chest wall, spine, or long bones). As SAPHO/CRMO are diagnoses of exclusion, the diagnoses might be difficult if skin manifestations are not clearly evident. However, knowledge of the imaging findings of skeletal disorders is helpful for correcting the diagnosis and avoiding unnecessary invasive procedures, as well as in facilitating early diagnosis and adequate treatment. This pictorial review describes the appearance of increased skeletal uptake for SAPHO/CRMO on bone scintigraphy along with findings from radiography, computed tomography, and magnetic resonance imaging.

中文翻译:

SAPHO/CRMO 患者的影像特征:图片回顾。

滑膜炎、痤疮、脓疱病、骨质增生和骨炎 (SAPHO) 综合征和慢性复发性多灶性骨髓炎 (CRMO) 已被描述为经常与皮肤表现相关的慢性骨关节炎炎症疾病,而 SAPHO 和 CRMO (SAPHO/CRMO) 是罕见的自身炎症性疾病病因不明。SAPHO 倾向于发生在成人中,而 CRMO 主要发生在儿童和青少年中。SAPHO/CRMO 可以影响任何骨骼区域(例如,前胸壁、脊柱或长骨)。由于 SAPHO/CRMO 是排除性诊断,如果皮肤表现不明显,诊断可能会很困难。然而,了解骨骼疾病的影像学表现有助于纠正诊断和避免不必要的侵入性操作,以及促进早期诊断和适当治疗。
更新日期:2020-04-30
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