Advanced magnetic resonance spectroscopic neuroimaging: Experts' consensus recommendations,NMR in Biomedicine

当前位置： X-MOL 学术 › NMR Biomed. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Advanced magnetic resonance spectroscopic neuroimaging: Experts' consensus recommendations
NMR in Biomedicine ( IF 2.7 ) Pub Date : 2020-04-29 , DOI: 10.1002/nbm.4309
Andrew A Maudsley ₁ , Ovidiu C Andronesi ₂ , Peter B Barker ₃ , Alberto Bizzi ₄ , Wolfgang Bogner ₅ , Anke Henning _{6,

7} , Sarah J Nelson ₈ , Stefan Posse ₉ , Dikoma C Shungu ₁₀ , Brian J Soher ₁₁

Affiliation

Department of Radiology, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Department of Radiology, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Boston, Massachusetts.
The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, and the Kennedy Krieger Institute, F.M. Kirby Center for Functional Brain Imaging, Baltimore, Maryland.
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University Vienna, Vienna, Austria.
Max Planck Institute for Biological Cybernetics, Tübingen, Germany.
Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas.
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
Department of Neurology, University of New Mexico, Albuquerque, New Mexico.
Department of Neuroradiology, Weill Cornell Medical College, New York, New York.
Department of Radiology, Duke University Medical Center, Durham, North Carolina.

Magnetic resonance spectroscopic imaging (MRSI) offers considerable promise for monitoring metabolic alterations associated with disease or injury; however, to date, these methods have not had a significant impact on clinical care, and their use remains largely confined to the research community and a limited number of clinical sites. The MRSI methods currently implemented on clinical MRI instruments have remained essentially unchanged for two decades, with only incremental improvements in sequence implementation. During this time, a number of technological developments have taken place that have already greatly benefited the quality of MRSI measurements within the research community and which promise to bring advanced MRSI studies to the point where the technique becomes a true imaging modality, while making the traditional review of individual spectra a secondary requirement. Furthermore, the increasing use of biomedical MR spectroscopy studies has indicated clinical areas where advanced MRSI methods can provide valuable information for clinical care. In light of this rapidly changing technological environment and growing understanding of the value of MRSI studies for biomedical studies, this article presents a consensus from a group of experts in the field that reviews the state‐of‐the‐art for clinical proton MRSI studies of the human brain, recommends minimal standards for further development of vendor‐provided MRSI implementations, and identifies areas which need further technical development.

中文翻译：

先进的磁共振波谱神经影像：专家的共识建议

磁共振波谱成像（MRSI）为监测与疾病或损伤相关的代谢变化提供了广阔的前景；然而，迄今为止，这些方法尚未对临床护理产生重大影响，其使用仍然主要局限于研究界和数量有限的临床场所。目前在临床 MRI 仪器上实施的 MRSI 方法二十年来基本保持不变，仅在序列实施方面进行了逐步改进。在此期间，发生了许多技术发展，这些发展已经极大地提高了研究界内 MRSI 测量的质量，并有望将先进的 MRSI 研究带到使该技术成为真正的成像模式的地步，同时使传统的 MRSI 测量成为可能。审查单个光谱是次要要求。此外，生物医学 MR 波谱研究的越来越多的使用表明先进 MRSI 方法可以为临床护理提供有价值的信息的临床领域。鉴于这种快速变化的技术环境以及对 MRSI 研究对生物医学研究价值的日益了解，本文提出了该领域专家组的共识，回顾了临床质子 MRSI 研究的最新技术人脑，建议进一步开发供应商提供的 MRSI 实现的最低标准，并确定需要进一步技术开发的领域。

更新日期：2020-04-29

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11