The gold standard for measuring blood‐retinal barrier permeability is the Evans blue assay. However, this technique has limitations in vivo, including non‐specific tissue binding and toxicity. This study describes a non‐toxic, high‐throughput, and cost‐effective alternative technique that minimizes animal usage.

中文翻译：

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糖尿病大鼠模型视网膜通透性的非侵入性测量。

测量血-视网膜屏障通透性的金标准是伊文思蓝试验。然而，该技术在体内存在局限性，包括非特异性组织结合和毒性。本研究描述了一种无毒、高通量且具有成本效益的替代技术，可最大限度地减少动物使用。