The proteolipid protein (PLP) is the most abundant protein in the myelin sheath of the central nervous system (CNS). The gene coding PLP, proteolipid protein 1 (Plp1 ) is highly expressed in oligodendrocytes, the myelin‐forming cells in the CNS. Previous studies demonstrate that Plp1 gene is expressed in the embryonic CNS much earlier before the generation of oligodendrocytes. However, the progenitor identity and the fate of Plp1‐ expressing cells are still elusive.

中文翻译：

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胚胎小鼠脊髓中蛋白脂蛋白 1 基因 (Plp1) 表达细胞的身份和谱系命运。

蛋白脂蛋白 (PLP) 是中枢神经系统 (CNS) 髓鞘中含量最丰富的蛋白质。编码 PLP 的基因，蛋白脂蛋白 1 ( Plp1 ) 在少突胶质细胞中高度表达，少突胶质细胞是中枢神经系统的髓鞘形成细胞。以前的研究表明Plp1基因在少突胶质细胞产生之前更早地在胚胎中枢神经系统中表达。然而，表达Plp1的细胞的祖先身份和命运仍然难以捉摸。