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Tissue-specific expression of ribosomal protein paralogue eRpL22-like in Drosophila melanogaster eye development.
Developmental Dynamics ( IF 2.0 ) Pub Date : 2020-04-30 , DOI: 10.1002/dvdy.185
Brett W Gershman 1 , Caroline E Pritchard 1 , Kenneth P Chaney 2 , Vassie C Ware 1
Affiliation  

Differences in core or tissue‐specific ribosomal protein (Rp) composition within ribosomes contribute to ribosome heterogeneity and functional variability. Yet, the degree to which ribosome heterogeneity modulates development is unknown. The Drosophila melanogaster eRpL22 family contains structurally diverse paralogues, eRpL22 and eRpL22‐like. Unlike ubiquitously expressed eRpL22, eRpL22‐like expression is tissue‐specific, notably within the male germline and the eye. We investigated expression within the developing eye to uncover tissue/cell types where specific paralogue roles might be defined.

中文翻译:


核糖体蛋白旁系同源物 eRpL22 样在果蝇眼睛发育中的组织特异性表达。



核糖体内核心或组织特异性核糖体蛋白(Rp)组成的差异导致核糖体异质性和功能变异性。然而,核糖体异质性调节发育的程度尚不清楚。果蝇eRpL22 家族包含结构多样的旁系同源物、eRpL22 和 eRpL22-like。与普遍表达的 eRpL22 不同,eRpL22 样表达具有组织特异性,特别是在雄性种系和眼睛内。我们研究了发育中眼睛内的表达,以揭示可能定义特定旁系同源作用的组织/细胞类型。
更新日期:2020-04-30
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