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Morphometric analysis of alpha-1, 3-galactosyltransferase knockout pig kidney and heart.
Laboratory Animals ( IF 1.3 ) Pub Date : 2020-04-21 , DOI: 10.1177/0023677220915218
Bala Murali Krishna Vasamsetti 1 , Sang Hyoun Park 1 , Harikrishna Reddy Rallabandi 1 , Heasun Lee 1 , Sung-June Byun 1 , Sun A Ock 1 , Hwi-Cheul Lee 1 , Seongsoo Hwang 1 , Keon Bong Oh 1
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We report a morphometric evaluation of α1,3-galactosyltransferase knockout (GTKO) pig heart and kidney (n = 9) at the end of one, three and seven months. Organs parameters gradually increased with the age (p < 0.05) and body weight (p < 0.05) of the pigs. Organs morphometries were significantly correlated to the age and body weight of the animal. We were able to conclude the average size of GTKO pig heart and kidney based on age and body weight, which could be helpful in estimating the size of these organs non-invasively for transplantation.



中文翻译:

α-1、3-半乳糖基转移酶基因敲除猪肾脏和心脏的形态计量学分析。

我们 在一个月,三个月和七个月结束时报告了α1,3-半乳糖基转移酶敲除(GTKO)猪心脏和肾脏的形态计量学评估(n = 9)。 猪的器官参数随着年龄(p  <0.05)和体重(p <0.05)而逐渐增加。器官的形态与动物的年龄和体重显着相关。我们能够根据年龄和体重得出GTKO猪心和肾的平均大小,这可能有助于无创估计移植这些器官的大小。

更新日期:2020-04-21
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