Abstract The Amaryllidaceae family is widely distributed in different regions of the neotropics and temperate areas of the world. Species of the subfamily Amaryllidoideae are unique in producing the alkaloid galanthamine, which inhibits the action of acetylcholinesterase and is used for the treatment of Alzheimer's disease. In Peru, 15 genera and 68 species belonging to the Amaryllidoideae have been reported in different types of forest, ranging from wet montane to dry, as well as the sandy biomes of the Pacific coastal region, with the greatest diversity in the south. In the tribe Eustephieae, the Andean genus Pyrolirion Herb has eight species, six of which are endemic to Peru. In this work, the leaves and bulbs of Pyrolirion albicans were analyzed for their alkaloid content for the first time, using gas chromatography (GC) coupled to mass spectrometry (MS). The alkaloids determined in the leaves were galanthamine, chlidanthine, tazettine and lycorine and those in the bulbs were galanthamine, N-demethylgalanthamine, vittatine/crinine, montanine, pancracine, sternbergine, lycorine and hippeastrine. Owing to their important bioactive properties, the high quantity of montanine and galanthamine determined in the bulbs is of particular interest.

中文翻译：

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Pyrolirion albicans Herb 中的生物碱概况。（石蒜科），秘鲁特有种

摘要 石蒜科广泛分布于世界新热带和温带不同地区。石蒜亚科的物种在生产生物碱加兰他敏方面是独一无二的，加兰他敏抑制乙酰胆碱酯酶的作用，用于治疗阿尔茨海默病。在秘鲁，在不同类型的森林（从潮湿的山地到干燥的森林）以及太平洋沿海地区的沙质生物群落中，已报道了属于石蒜科的 15 属和 68 种物种，其中南部的多样性最大。在 Eusstephieae 部落中，安第斯山属 Pyrolirion Herb 有 8 种，其中 6 种是秘鲁特有的。在这项工作中，首次分析了 Pyrolirion albicans 的叶子和球茎的生物碱含量，使用气相色谱 (GC) 与质谱 (MS) 联用。叶子中测定的生物碱是雪花胺、花青素、tazettine 和石蒜碱，球茎中的生物碱是雪花胺、N-去甲基雪花胺、vittatine/crinine、山梨碱、pancracine、sternbergine、石蒜碱和hippeastrine。由于其重要的生物活性特性，在球茎中测定的大量褐煤碱和加兰他敏特别令人感兴趣。