The use of synthetic hormones to regulate sexual maturity in captive fish is a common practice. With aquaculture practices, fish production is desired throughout the year, necessitating the maintenance of quality standards, mainly regarding the characteristics of the fish produced. Embryonic development may be affected by toxins in the environment and by a variety of pathologies. The aim of this study was to determine the effects of treatment with gonadotropin-releasing hormone analog (GnRHa) on captive male and female Atlantic Salmon (Salmo salar) broodstock, observing the effects on the hormonal milieu and impacts on breeding outcomes. Sexually mature fish were fertilized with and without imposing a GnRHa treatment to evaluate the development of offspring up to the fry stage. The concentrations of 17β-estradiol (E2) and testosterone (T) were determined using commercially available ELISA kits. The results indicate the administration of GnRHa had marked effects on reductions of morphological deformities in the offspring and promoted development during the larval stage by inducing sexual maturity in both treated parents. The E2/T ratio results indicate the presence of endocrine disruptors. It is concluded that the use of GnRHa at a dose of 10 ug/kg in captive male and female Atlantic salmon broodstock has an inhibitory effect on the impacts of endocrine disruptors, does not affect fertilization rate, and has positive effects on development of offspring by reducing the number of morphological deformities during the larval stage of development.

中文翻译：

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大西洋鲑亲鱼的GnRHa处理可抑制内分泌干扰物的作用，从而提高后代质量。

使用合成激素来调节圈养鱼的性成熟是一种常见的做法。根据水产养殖的惯例，全年都需要进行鱼类生产，因此必须维持质量标准，主要是关于所生产鱼类的特性。胚胎发育可能受到环境中毒素和多种病理的影响。这项研究的目的是确定用促性腺激素释放激素类似物（GnRHa）处理对圈养的雄性和雌性大西洋鲑（Salmo salar）亲鱼的影响，观察对激素环境的影响以及对繁殖结果的影响。对有性成熟的鱼施肥，不施以GnRHa处理，以评估直至鱼苗阶段的后代发育。使用市售的ELISA试剂盒确定17β-雌二醇（E2）和睾丸激素（T）的浓度。结果表明，GnRHa的施用通过诱导两个接受治疗的父母的性成熟，对减少后代的形态畸形和在幼虫期促进发育具有显着效果。E2 / T比结果表明存在内分泌干扰物。结论是，在圈养的雄性和雌性大西洋鲑鱼亲鱼中以10 ug / kg的剂量使用GnRHa对内分泌干扰物的影响具有抑制作用，不影响受精率，并且对后代的发育有积极作用减少幼体发育阶段的形态畸形数量。结果表明，通过在两个接受治疗的父母中诱导性成熟，GnRHa的施用对减少后代的形态畸形和促进幼虫期的发育具有显著作用。E2 / T比结果表明存在内分泌干扰物。结论是，在圈养的雄性和雌性大西洋鲑鱼亲鱼中以10 ug / kg的剂量使用GnRHa对内分泌干扰物的影响有抑制作用，不影响受精率，并且对后代的发育有积极作用减少幼体发育阶段的形态畸形数量。结果表明，GnRHa的施用通过诱导两个接受治疗的父母的性成熟，对减少后代的形态畸形和在幼虫期促进发育具有显着效果。E2 / T比结果表明存在内分泌干扰物。结论是，在圈养的雄性和雌性大西洋鲑鱼亲鱼中以10 ug / kg的剂量使用GnRHa对内分泌干扰物的影响具有抑制作用，不影响受精率，并且对后代的发育有积极作用减少幼体发育阶段的形态畸形数量。E2 / T比结果表明存在内分泌干扰物。结论是，在圈养的雄性和雌性大西洋鲑鱼亲鱼中以10 ug / kg的剂量使用GnRHa对内分泌干扰物的影响具有抑制作用，不影响受精率，并且对后代的发育有积极作用减少幼体发育阶段的形态畸形数量。E2 / T比结果表明存在内分泌干扰物。结论是，在圈养的雄性和雌性大西洋鲑鱼亲鱼中以10 ug / kg的剂量使用GnRHa对内分泌干扰物的影响具有抑制作用，不影响受精率，并且对后代的发育有积极作用减少幼体发育阶段的形态畸形数量。