Objective

To retrospectively analyse the anaesthetic management, complications and haemodynamic changes in a cohort of dogs undergoing transvascular patent ductus arteriosus (PDA) occlusion in a tertiary referral centre (from January 2017 to August 2018).

Study design

Retrospective study.

Animals

A total of 49 client-owned dogs.

Methods

Anaesthetic records of dogs with PDA that underwent transvascular occlusion of the ductus were reviewed. Anaesthetic complications evaluated included tachycardia [heart rate (HR) > 160 beats minute^–1], bradycardia (HR < 50 beats minute^–1), hypertension [systolic arterial pressure (SAP) > 150 mmHg], hypotension [mean arterial pressure (MAP) < 60 mmHg], hypothermia (<37 °C) and the presence of arrhythmias. Cardiovascular variables [HR and invasive SAP, MAP and diastolic arterial pressure (DAP)] at the time of occlusion device deployment (time 0) were compared with variables at 5 and 10 minutes after deployment. Descriptive statistics, Shapiro–Wilk test and repeated measures analysis of variance followed by a Dunnett’s post hoc test were used to analyse the data (p < 0.05).

Results

Crossbreed dogs were the most commonly represented followed by the Cavalier King Charles Spaniel. The median age was 8 (2–108) months, and female dogs were over-represented (65.3%). The most common American Society of Anesthesiologists score was III. Mean duration of anaesthesia was 96 ± 26 minutes and mean surgery time was 58 ± 21 minutes. Acepromazine with methadone was the most commonly used premedication combination (77.6%). Propofol was the most common induction agent (73.5%). General anaesthesia was maintained with isoflurane in oxygen in all dogs. Complications included hypotension (63%), hypothermia (34%), bradycardia (28%), arrhythmias (16%), hypertension (16%) and haemorrhage (2%). MAP and DAP increased significantly 10 minutes after device deployment compared with time 0.

Conclusions

and clinical relevance: Hypotension was the most common complication reported in dogs undergoing transvascular PDA occlusion. No major adverse events were documented.

中文翻译：

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犬经血管动脉导管未闭的麻醉处理和并发症。

目的

为了回顾性分析三级转诊中心（2017年1月至2018年8月）接受跨血管动脉导管未闭（PDA）的犬群的麻醉管理，并发症和血流动力学变化。

学习规划

回顾性研究。

动物

共有49只客户拥有的狗。

方法

回顾了经导管经导管阻塞的PDA犬的麻醉记录。评估的麻醉并发症包括心动过速[心率（HR）> 160次/分^–1 ]，心动过缓（HR <50次/分^–1），高血压[收缩压（SAP）> 150 mmHg]，低血压[平均动脉压（MAP） ）<60 mmHg]，体温过低（<37°C）和存在心律不齐。将闭塞器械部署时（时间0）的心血管变量[HR和有创SAP，MAP和舒张压（DAP）]与部署后5分钟和10分钟的变量进行比较。描述性统计，Shapiro-Wilk检验和方差的重复测量分析，然后进行Dunnett事后分析检验用于分析数据（p <0.05）。

结果

杂种犬是最常见的代表，其次是骑士国王查尔斯猎犬。中位年龄为8（2–108）个月，而雌狗的比例过高（65.3％）。美国麻醉医师学会最常见的分数是III。平均麻醉时间为96±26分钟，平均手术时间为58±21分钟。乙酰丙嗪与美沙酮是最常用的处方药组合（77.6％）。异丙酚是最常见的诱导剂（73.5％）。在所有的狗中，用氧中的异氟烷维持全身麻醉。并发症包括低血压（63％），体温过低（34％），心动过缓（28％），心律不齐（16％），高血压（16％）和出血（2％）。与时间0相比，设备部署10分钟后，MAP和DAP显着增加。

结论

和临床意义：低血压是经血管PDA闭塞的犬中最常见的并发症。没有重大不良事件的记录。