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Anaesthetic management and complications of transvascular patent ductus arteriosus occlusion in dogs.
Veterinary Anaesthesia and Analgesia ( IF 1.4 ) Pub Date : 2020-04-20 , DOI: 10.1016/j.vaa.2020.01.009
Carmelo Parisi 1 , Victoria Phillips 1 , Jacques Ferreira 1 , Chris Linney 1 , Alastair Mair 1
Affiliation  

Objective

To retrospectively analyse the anaesthetic management, complications and haemodynamic changes in a cohort of dogs undergoing transvascular patent ductus arteriosus (PDA) occlusion in a tertiary referral centre (from January 2017 to August 2018).

Study design

Retrospective study.

Animals

A total of 49 client-owned dogs.

Methods

Anaesthetic records of dogs with PDA that underwent transvascular occlusion of the ductus were reviewed. Anaesthetic complications evaluated included tachycardia [heart rate (HR) > 160 beats minute–1], bradycardia (HR < 50 beats minute–1), hypertension [systolic arterial pressure (SAP) > 150 mmHg], hypotension [mean arterial pressure (MAP) < 60 mmHg], hypothermia (<37 °C) and the presence of arrhythmias. Cardiovascular variables [HR and invasive SAP, MAP and diastolic arterial pressure (DAP)] at the time of occlusion device deployment (time 0) were compared with variables at 5 and 10 minutes after deployment. Descriptive statistics, Shapiro–Wilk test and repeated measures analysis of variance followed by a Dunnett’s post hoc test were used to analyse the data (p < 0.05).

Results

Crossbreed dogs were the most commonly represented followed by the Cavalier King Charles Spaniel. The median age was 8 (2–108) months, and female dogs were over-represented (65.3%). The most common American Society of Anesthesiologists score was III. Mean duration of anaesthesia was 96 ± 26 minutes and mean surgery time was 58 ± 21 minutes. Acepromazine with methadone was the most commonly used premedication combination (77.6%). Propofol was the most common induction agent (73.5%). General anaesthesia was maintained with isoflurane in oxygen in all dogs. Complications included hypotension (63%), hypothermia (34%), bradycardia (28%), arrhythmias (16%), hypertension (16%) and haemorrhage (2%). MAP and DAP increased significantly 10 minutes after device deployment compared with time 0.

Conclusions

and clinical relevance: Hypotension was the most common complication reported in dogs undergoing transvascular PDA occlusion. No major adverse events were documented.



中文翻译:

犬经血管动脉导管未闭的麻醉处理和并发症。

目的

为了回顾性分析三级转诊中心(2017年1月至2018年8月)接受跨血管动脉导管未闭(PDA)的犬群的麻醉管理,并发症和血流动力学变化。

学习规划

回顾性研究。

动物

共有49只客户拥有的狗。

方法

回顾了经导管经导管阻塞的PDA犬的麻醉记录。评估的麻醉并发症包括心动过速[心率(HR)> 160次/分–1 ],心动过缓(HR <50次/分–1),高血压[收缩压(SAP)> 150 mmHg],低血压[平均动脉压(MAP) )<60 mmHg],体温过低(<37°C)和存在心律不齐。将闭塞器械部署时(时间0)的心血管变量[HR和有创SAP,MAP和舒张压(DAP)]与部署后5分钟和10分钟的变量进行比较。描述性统计,Shapiro-Wilk检验和方差的重复测量分析,然后进行Dunnett事后分析检验用于分析数据(p <0.05)。

结果

杂种犬是最常见的代表,其次是骑士国王查尔斯猎犬。中位年龄为8(2–108)个月,而雌狗的比例过高(65.3%)。美国麻醉医师学会最常见的分数是III。平均麻醉时间为96±26分钟,平均手术时间为58±21分钟。乙酰丙嗪与美沙酮是最常用的处方药组合(77.6%)。异丙酚是最常见的诱导剂(73.5%)。在所有的狗中,用氧中的异氟烷维持全身麻醉。并发症包括低血压(63%),体温过低(34%),心动过缓(28%),心律不齐(16%),高血压(16%)和出血(2%)。与时间0相比,设备部署10分钟后,MAP和DAP显着增加。

结论

和临床意义:低血压是经血管PDA闭塞的犬中最常见的并发症。没有重大不良事件的记录。

更新日期:2020-04-20
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