Fine needle aspiration cytology (FNAC ) is a widely accepted safe, simple and rapid diagnostic procedure used in the examination of neoplastic and non‐neoplastic lesions of various locations. Since its introduction, FNAC has developed into an effective diagnostic tool practiced in a large majority of medical centres evaluating and treating oncological patients. The role of FNAC has been limited in the examination of primary soft tissue lesions, however, as many physicians working in this area recommended against using FNAC . An increasing use of minimally invasive diagnostic procedures in the last decade has resulted in a better acceptance of FNAC as a first‐line approach or as a complementary tool to core needle biopsy in the diagnosis of musculoskeletal lesions. This review discusses the role and value of FNAC in the evaluation and treatment of soft tissue tumours based on the experience gathered over the course of 48 years at the Sarcoma Center in Lund, Sweden. FNAC reports most often provide diagnostic information allowing the initiation of treatment or, when definitive diagnosis cannot be rendered from a cytological examination, guiding the continued diagnostic investigation. The main advantages of soft tissue FNAC are good sensitivity and specificity, low morbidity, speed of diagnosis, and low cost/benefit ratio. The most important disadvantages stem from limited experience in cytological diagnosis of soft tissue tumours and a lack of standardised and uniform reporting system for soft tissue FNAC .

中文翻译：

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细针穿刺细胞学在软组织肿瘤诊断中的作用。

细针穿刺细胞学（FNAC）是一种被广泛接受的安全、简单和快速的诊断程序，用于检查不同部位的肿瘤和非肿瘤病变。自推出以来，FNAC 已发展成为大多数评估和治疗肿瘤患者的医疗中心实践的有效诊断工具。FNAC 在检查原发性软组织病变方面的作用受到限制，但是，因为许多在该领域工作的医生建议不要使用 FNAC。在过去的十年中，越来越多地使用微创诊断程序，这使得 FNAC 作为一线方法或作为诊断肌肉骨骼病变的空心针活检的补充工具得到了更好的接受。本综述根据瑞典隆德肉瘤中心 48 年来积累的经验，讨论了 FNAC 在评估和治疗软组织肿瘤中的作用和价值。FNAC 报告通常提供诊断信息，允许开始治疗，或者当细胞学检查无法做出明确诊断时，指导继续的诊断调查。软组织 FNAC 的主要优点是良好的敏感性和特异性、低发病率、诊断速度和低成本/收益比。最重要的缺点源于在软组织肿瘤细胞学诊断方面的经验有限，以及软组织 FNAC 缺乏标准化和统一的报告系统。