Abstract Polyelectrolyte complexes (PECs) are widely used in systems for the release of drugs, fertilizers as well as in the surface modification of fibers and particles. In this work, PEC dispersions were produced from chitosan (CS), a cationic biopolymer, and an anionic cyclodextrin (carboxymethylated--cyclodextrin, CM-β-CD, synthesized in this work), in order to obtain particles with polar regions, around the ionic crosslinking sites, and hydrophobic regions from cyclodextrin molecules internal cavities. Bulk materials were characterized by FTIR, XRD, TGA, and MALDI-TOF. PEC dispersions were additionally characterized by viscometry, zeta potential measurements, and DLS. Apart from the usual loss of crystallinity observed as PEC is formed, in the specific case of CS/CM-β-CD complex a drastic formation of dispersed solid phase was observed, without the detection of an initial decrease of macromolecular dimensions of soluble macromolecular species. This unusual behavior was associated to the high degree of substitution of the CM-β-CD prepared in this work. Graphical Abstract

中文翻译：

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羧甲基化-β-环糊精/壳聚糖颗粒：散装固体和水分散体

摘要 聚电解质复合物 (PEC) 广泛用于药物、肥料的释放系统以及纤维和颗粒的表面改性。在这项工作中，PEC 分散体由壳聚糖 (CS)、阳离子生物聚合物和阴离子环糊精（羧甲基化--环糊精，CM-β-CD，在这项工作中合成）制备，以获得具有极性区域的粒子，在离子交联位点和环糊精分子内腔的疏水区域。散装材料通过 FTIR、XRD、TGA 和 MALDI-TOF 进行表征。PEC 分散体还通过粘度测定、zeta 电位测量和 DLS 进行表征。除了在形成 PEC 时观察到的通常结晶度损失之外，在 CS/CM-β-CD 复合物的特定情况下，观察到分散固相的急剧形成，没有检测到可溶性大分子物质的大分子尺寸的初始降低。这种不寻常的行为与本工作中制备的 CM-β-CD 的高度取代有关。图形概要