We recently developed a new light source that allows for the continuous monitoring of light-induced changes using common spectrophotometric devices adapted for microplate analyses. This source was designed primarily to induce photodynamic processes in cell models. Modern light components, such as LED chips, were used to improve the irradiance homogeneity. In addition, this source forms a small hermetic chamber and thus allows for the regulation of the surrounding atmosphere, which plays a significant role in these light-dependent reactions. The efficacy of the new light source was proven via kinetic measurements of reactive oxygen species generated during the photodynamic reaction of chloroaluminium phthalocyanine disulfonate (ClAlPcS 2 ) in three cell lines: human melanoma cells (G361), human breast adenocarcinoma cells (MCF7), and human fibroblasts (BJ).

中文翻译：

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用于诱导和监测体外光动力过程的新型平面光源

我们最近开发了一种新光源，可以使用适用于微孔板分析的常见分光光度计设备连续监测光引起的变化。该光源主要设计用于在细胞模型中诱导光动力过程。现代光组件，如 LED 芯片，被用来改善辐照均匀性。此外，该光源形成一个小的密封室，因此可以调节周围的大气，这在这些依赖光的反应中起着重要作用。通过对氯铝酞菁二磺酸盐 (ClAlPcS 2 ) 在三种细胞系中的光动力反应过程中产生的活性氧进行动力学测量，证明了新光源的功效：人黑色素瘤细胞 (G361)、人乳腺癌细胞 (MCF7)、