Abstract

A method has been developed for the synthesis of calcium carbonate particles with the use of mesoporous silica particles as a template. Hydrosols of the synthesized CaCO₃ particles are unstable with respect to aggregation at neutral pH values and coagulate to yield aggregates with submicron sizes. A procedure of electrostatic stabilization by adding an aqueous FeCl₃ solution has been proposed for the preparation of aggregatively stable hydrosols. It has been shown that this procedure of stabilization leads to the peptization of the aggregates and makes it possible to obtain individual calcium carbonate nanoparticles with sizes of 50−80 nm. The obtained CaCO₃ nanoparticles are porous, thereby making it possible to use their stable hydrosols in medicine.

中文翻译：

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模板法合成碳酸钙纳米粒子水溶胶的静电稳定性

摘要

已经开发出一种以中孔二氧化硅颗粒为模板合成碳酸钙颗粒的方法。合成的CaCO ₃颗粒的水溶胶在中性pH值下相对于聚集是不稳定的，并且会凝结形成亚微米尺寸的聚集体。已经提出了通过添加FeCl ₃水溶液来进行静电稳定的方法，以用于制备总体稳定的水溶胶。已经表明，这种稳定过程导致聚集体胶溶化，并使得有可能获得尺寸为50-80 nm的单个碳酸钙纳米颗粒。所获得的CaCO ₃纳米颗粒是多孔的，从而使得可以将其稳定的水溶胶用于医学中。