Hyptis Jacq. (Lamiaceae) has been used in traditional medicine for the treatment of many diseases around the world. However, Harley and Pastore in 2012 proposed a new circumscription for this large genus, reducing its number of species, but supporting its monophyly. Hyptis and Peltodon were used as keywords, and triage of articles was performed using genus delimitation sensu Harley and Pastore. Only 29 species have some type of record in the literature for their medicinal use and chemical description, corresponding to 20% of the 148 species. Most cited biological activities were the antioxidant activity, reported for 9% of the species, and the antifungal activity reported for 5% of the species. For 11% of the species was described the essential oil composition, while non-volatile compounds were reported for only 6% of them. Terpenes, flavonoids, and caffeic acid derivatives are the most reported compounds for this genus. Only 8% of the species are reported as medicinal, with potential as antibacterial and antiparasitic, pointing to relevance of Hyptis to bioprospecting studies, especially in South America and Africa. However, there is a lack of studies regarding isolated compounds concerning their toxicology and efficacy, important information to achieve the production and the effective use of Hyptis as a herbal medicine.

中文翻译：

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Hyptis Jacq. 的植物化学分析和生物活性综述：巴西原生唇形科植物属

海普提斯·雅克。（唇形科）已在传统医学中用于治疗世界各地的许多疾病。然而，哈雷和帕斯托雷在 2012 年为这个大属提出了一个新的限制，减少了它的物种数量，但支持了它的单系。Hyptis 和 Peltodon 被用作关键词，文章的分类是使用属定界意义 Harley 和 Pastore 进行的。只有 29 个物种在文献中对其药用和化学描述有某种类型的记录，对应于 148 个物种的 20%。引用最多的生物活性是抗氧化活性，据报道有 9% 的物种具有抗真菌活性，据报道有 5% 的物种具有抗真菌活性。11% 的物种被描述为精油成分，而非挥发性化合物仅被报道为 6%。萜类、类黄酮、和咖啡酸衍生物是该属中报道最多的化合物。只有 8% 的物种被报告为药用，具有抗菌和抗寄生虫的潜力，这表明 Hyptis 与生物勘探研究的相关性，尤其是在南美洲和非洲。然而，缺乏关于分离化合物的毒理学和功效、实现 Hyptis 作为草药的生产和有效使用的重要信息的研究。