Radon therapy has been traditionally performed globally for oxidative stress-related diseases. Many researchers have studied the beneficial effects of radon exposure in living organisms. However, the effects of thoron, a radioisotope of radon, have not been fully examined. In this study, we aimed to compare the biological effects of radon and thoron inhalation on mouse organs with a focus on oxidative stress. Male BALB/c mice were randomly divided into 15 groups: sham inhalation, radon inhalation at a dose of 500 Bq/m3 or 2000 Bq/m3, and thoron inhalation at a dose of 500 Bq/m3 or 2000 Bq/m3 were carried out. Immediately after inhalation, mouse tissues were excised for biochemical assays. The results showed a significant increase in superoxide dismutase and total glutathione, and a significant decrease in lipid peroxide following thoron inhalation under several conditions. Additionally, similar effects were observed for different doses and inhalation times between radon and thoron. Our results suggest that thoron inhalation also exerts antioxidative effects against oxidative stress in organs. However, the inhalation conditions should be carefully analyzed because of the differences in physical characteristics between radon and thoron.

中文翻译：

---

ra和气吸入对小鼠器官的抗氧化作用比较。

传统上，globally气疗法已在全球范围内用于治疗氧化应激相关疾病。许多研究人员已经研究了exposure在活生物体中的有益作用。然而，tho的一种放射性同位素ron的作用尚未得到充分检验。在这项研究中，我们旨在比较ra和气吸入对小鼠器官的生物学效应，重点是氧化应激。将雄性BALB / c小鼠随机分为15组：假吸入，以500 Bq / m3或2000 Bq / m3的剂量吸入ra和以500 Bq / m3或2000 Bq / m3的剂量进行tho酮吸入。吸入后，立即切除小鼠组织进行生化分析。结果表明，超氧化物歧化酶和总谷胱甘肽显着增加，在几种条件下吸入甲之后，脂质过氧化物的显着降低。此外，for和之间的不同剂量和吸入时间观察到相似的效果。我们的研究结果表明，吸入ron酮还可以对器官中的氧化应激产生抗氧化作用。但是，由于ra和tho的物理特性不同，应仔细分析吸入条件。