In this paper, a Kretschmann configuration based surface plasmon resonance (SPR) sensor is numerically designed using graphene-MoS₂ hybrid structure TiO₂-SiO₂ nano particles for formalin detection. In this design, the observations of SPR angle versus minimum reflectance and SPR frequency (F_SPR) versus maximum transmittance (T_max) are considered. The chitosan is used as probe legend to perform reaction with the formalin (40% formaldehyde) which acts as target legend. In this paper, both graphene and MoS₂ are used as biomolecular acknowledgment element (BAE) and TiO₂ as well as SiO₂ bilayers is used to improve the sensitivity of the sensor. The numerical results show that the variation of FSPR and SPR angles for inappropriate sensing of formalin is quite insignificant which confirms the absence of formalin. On the other hand, these variations for appropriate sensing are considerably significant that confirm the presence of formalin. At the end of this article, the variation of sensitivity of the proposed biosensor is measured in corresponding to the increment of a refractive index with a refractive index step 0.01 refractive index unit (RIU). In inclusion of TiO₂-SiO₂ bilayers with graphene-MoS₂, a maximum sensitivity of 85.375% is numerically calculated.

中文翻译：

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设计基于Kretschmann构型的TiO 2 -SiO 2纳米折射率石墨烯-MoS 2杂化层的数值方法

在本文中，使用石墨烯-MoS ₂杂化结构的TiO ₂ -SiO ₂纳米颗粒对福尔马林进行了数值设计，设计了基于Kretschmann构型的表面等离子体共振（SPR）传感器。在此设计中，考虑了SPR角度与最小反射率和SPR频率（F _SPR）与最大透射率（T _max）的关系。壳聚糖用作探针图例，与充当目标图例的福尔马林（40％甲醛）进行反应。在本文中，石墨烯和MoS ₂均用作生物分子确认元素（BAE），TiO ₂和SiO ₂双层用于提高传感器的灵敏度。数值结果表明，对于不适当的福尔马林感测，FSPR和SPR角度的变化很小，这证实了福尔马林的缺失。另一方面，这些用于适当感测的变化相当重要，证实了福尔马林的存在。在本文的结尾，提出的生物传感器的灵敏度变化是通过以折射率为0.01折射率单位（RIU）的折射率增量进行测量的。在夹杂物的TiO ₂ -SiO _2个双层石墨烯-MOS ₂，的85.375％的最大灵敏度数值计算。