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A novel herpesvirus in a white stork associated with splenic and hepatic necrosis.
The Journal of Veterinary Diagnostic Investigation ( IF 1.5 ) Pub Date : 2020-04-10 , DOI: 10.1177/1040638720915539
Zoe E Mack 1 , Christopher J Bonar 2 , Michael M Garner 3 , Maren J Connolly 2 , April L Childress 4 , James F X Wellehan 4
Affiliation  

We identified a novel herpesvirus in a captive juvenile white stork (Ciconia ciconia) that experienced progressive weight loss followed by death. Histologic findings included severe splenic and hepatic necrosis, and intranuclear inclusion bodies in hepatocytes and unidentified splenic cells. The virus was amplified, sequenced, and subsequently accessioned as Ciconiid alphaherpesvirus 1. Phylogenetic analysis was performed and revealed that this virus is more closely related to mammalian herpesviruses than those within the genus Mardivirus. Additional sequence of viruses in this area may elucidate the ancestral virus that jumped from reptilian to mammalian hosts.

中文翻译:

与脾脏和肝坏死相关的白鹳中的新型疱疹病毒。

我们在一只圈养的幼年白鹳 (Ciconia ciconia) 中发现了一种新型疱疹病毒,这种白鹳经历了逐渐的体重减轻,随后死亡。组织学发现包括严重的脾脏和肝坏死,以及肝细胞和身份不明的脾细胞中的核内包涵体。该病毒经过扩增、测序,随后被登记为 Ciconiid alphaherpesvirus 1。系统发育分析表明,与 Mardivirus 属相比,该病毒与哺乳动物疱疹病毒的关系更为密切。该区域的其他病毒序列可能会阐明从爬行动物宿主转移到哺乳动物宿主的祖先病毒。
更新日期:2020-04-10
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