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A retrospective histologic study of 140 cases of clinically significant equine ocular disorders.
The Journal of Veterinary Diagnostic Investigation ( IF 1.5 ) Pub Date : 2020-03-24 , DOI: 10.1177/1040638720912698
Mariana M Flores 1, 2, 3 , Fabio Del Piero 1, 2, 3 , Perry L Habecker 1, 2, 3 , Ingeborg M Langohr 1, 2, 3
Affiliation  

Ocular diseases are an important category in equine medicine; however, most articles regarding histologic ocular lesions in horses are exclusive to a specific condition and do not provide a complete review of clinically significant ocular disease frequency in a diagnostic laboratory. We reviewed sections of equine eyes from 140 cases (98 enucleations [biopsies] and 42 autopsies) with clinically relevant ocular alterations at 2 diagnostic centers in the United States. The most common primary conditions were non-traumatic keratitis (36), equine recurrent uveitis (ERU; 31), traumatic injuries (22), ocular and periocular neoplasms (19), and uveitis and/or endophthalmitis resulting from sepsis (18). Congenital anomalies (3) and retinal atrophy and detachment alone (3) were infrequent. Non-traumatic keratitis was frequently accompanied by anterior uveitis (22), corneal rupture (16), pre-iridal fibrovascular membrane formation (13), and secondary mycotic infection (11). ERU was the second and third most prevalent disease in autopsies and enucleations, respectively. This condition was commonly associated with glaucoma (15). Glaucoma (25) and cataract (20) were the most prevalent secondary alterations in the evaluated cases. Keratitis (20) and corneal rupture (16) were among the most prevalent consequences of trauma. Information presented herein may guide clinicians and pathologists, contributing to the early diagnosis of potentially vision-impairing conditions and raising the chances of successful treatment and cure.

中文翻译:

回顾性组织学研究140例具有临床意义的马眼疾病。

眼部疾病是马医学中的重要类别。但是,有关马的组织学性眼部病变的大多数文章仅针对特定情况,并没有在诊断实验室中全面审查具有临床意义的眼部疾病的发生频率。我们回顾了美国2个诊断中心的140例(98例摘除[活检]和42例尸检)的马眼部分,这些眼具有临床相关的眼球改变。最常见的主要疾病是非创伤性角膜炎(36),马复发性葡萄膜炎(ERU; 31),外伤(22),眼和眼周肿瘤(19)以及由败血症引起的葡萄膜炎和/或眼内炎(18)。先天性异常(3)和仅视网膜萎缩和脱离(3)很少见。非创伤性角膜炎常伴有前葡萄膜炎(22),角膜破裂(16),虹膜前纤维血管膜形成(13)和继发性真菌感染(11)。在尸检和摘除术中,ERU分别是第二和第三大流行的疾病。这种情况通常与青光眼有关(15)。在评估病例中,青光眼(25)和白内障(20)是最普遍的继发性改变。角膜炎(20)和角膜破裂(16)是创伤最普遍的后果。本文提供的信息可指导临床医生和病理学家,有助于早期诊断潜在的视力障碍状况,并增加成功治疗和治愈的机会。和继发性真菌感染(11)。在尸检和摘除术中,ERU分别是第二和第三大流行的疾病。这种情况通常与青光眼有关(15)。在评估病例中,青光眼(25)和白内障(20)是最普遍的继发性改变。角膜炎(20)和角膜破裂(16)是创伤最普遍的后果。本文提供的信息可指导临床医生和病理学家,有助于早期诊断潜在的视力障碍状况,并增加成功治疗和治愈的机会。和继发性真菌感染(11)。在尸检和摘除术中,ERU分别是第二大和第三大流行病。这种情况通常与青光眼有关(15)。在评估病例中,青光眼(25)和白内障(20)是最普遍的继发性改变。角膜炎(20)和角膜破裂(16)是创伤最普遍的后果。本文介绍的信息可指导临床医生和病理医生,有助于早期诊断潜在的视力障碍状况,并增加成功治疗和治愈的机会。角膜炎(20)和角膜破裂(16)是创伤最普遍的后果。本文介绍的信息可指导临床医生和病理医生,有助于早期诊断潜在的视力障碍状况,并增加成功治疗和治愈的机会。角膜炎(20)和角膜破裂(16)是创伤最普遍的后果。本文提供的信息可指导临床医生和病理学家,有助于早期诊断潜在的视力障碍状况,并增加成功治疗和治愈的机会。
更新日期:2020-03-24
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