To find an efficient control method for gizzard erosion (GE) caused by fowl adenovirus serotype 1 (FAdV-1) infection in poultry farms, we examined the virucidal effects of commercial disinfectants. In laboratory tests, the virucidal effects of the disinfectants calcium hydroxide (CHO), glutaraldehyde (GLT), orthodichlorobenzene, cresol, and didecyldimethylammonium chloride against FAdV-1s were examined. Among them, CHO and GLT were extremely effective in all tested viruses, even at low concentrations, under the condition of 20°C. However, virucidal effect under the condition of 4°C at low concentrations of GLT was attenuated. Then, in a broiler farm where GE in chickens continuously occurred, we applied 2 combinations of disinfectants on the inside and outside of poultry houses every “chicken-free” period after shipping of chickens. The disinfection effect was then evaluated by gizzard rejection rate in the next flock. We detected GE in the flocks after disinfection with a combination of GLT and CHO at an ambient temperature of approximately 11°C. Moreover, we detected GE in the flock after disinfecting with didecyldimethylammonium chloride and CHO, regardless of the environmental temperature. In contrast, we did not detect GE in the flock after disinfecting with GLT and CHO under the condition of ambient temperature of approximately 21°C. These findings underline the importance of performing thorough disinfection with effective disinfectants during the “chicken-free” downtime to prevent the persistence of GE caused by FAdV-1 infection. It is necessary to use liquid disinfectants such as GLT and to pay close attention to ambient temperatures and the working concentration of disinfectants.

为了找到一种有效的控制方法来控制家禽场中由禽腺病毒血清型1（FAdV-1）感染引起的g侵蚀（GE），我们研究了商用消毒剂的杀毒作用。在实验室测试中，消毒剂的杀菌作用为氢氧化钙（CHO），戊二醛（GLT）），检测了对二氯氯苯，甲酚和二癸基二甲基氯化铵对FAdV-1的作用。其中，CHO和GLT在所有测试的病毒中都非常有效，即使在20°C的条件下，即使在低浓度下也是如此。但是，在低浓度的GLT下于4℃条件下的杀病毒作用减弱。然后，在一个不断发生鸡中GE的肉鸡场中，在鸡运输后的每个“无鸡”时期，我们在禽舍的内部和外部都使用了2种消毒剂组合。然后通过下一组鸡g的排斥率评估其消毒效果。我们在大约11°C的环境温度下用GLT和CHO组合消毒后在鸡群中检测到GE。此外，无论环境温度如何，我们均用二癸基二甲基氯化铵和CHO消毒后在鸡群中检测到GE。相反，在大约21°C的环境温度下用GLT和CHO消毒后，我们没有在鸡群中检测到GE。这些发现强调了在“无鸡”停机期间用有效消毒剂进行彻底消毒的重要性，以防止由FAdV-1感染引起的GE持续存在。必须使用液体消毒剂，例如GLT，并密切注意环境温度和消毒剂的工作浓度。这些发现强调了在“无鸡”停机期间用有效消毒剂进行彻底消毒的重要性，以防止由FAdV-1感染引起的GE持续存在。必须使用液体消毒剂，例如GLT，并密切注意环境温度和消毒剂的工作浓度。这些发现强调了在“无鸡”停机期间用有效消毒剂进行彻底消毒的重要性，以防止由FAdV-1感染引起的GE持续存在。必须使用液体消毒剂，例如GLT，并密切注意环境温度和消毒剂的工作浓度。