Vaccination with live anticoccidial vaccine is widely practiced to control coccidiosis in broiler breeders. However, vaccination during feed restriction may affect early pullet growth. Two experiments were conducted using Cobb-500-FF broiler breeder female chicks to evaluate the level of immunity generated by a live anticoccidial vaccine and to study the effects of vaccination with low doses of Eimeria acervulina, Eimeria tenella, and Eimeria maxima on early growth of chicks during feed restriction. In the first experiment, unvaccinated and vaccinated chicks were allocated to battery cages at days postvaccination (DPV) 28, 35, 42, 49, and 56 and challenged with 100,000 oocysts of E. tenella. In the second experiment, a total of 280-day-old chicks were allocated to 2 groups and vaccinated with either 0 or 500 oocysts each of 3 species of Eimeria. Cecal gross lesion scores and dropping pan scores were significantly reduced (P < 0.05) in vaccinated groups at all time points in the first experiment suggesting that birds had acquired immunity against E. tenella challenge infection. In the second experiment, birds vaccinated with low doses of Eimeria showed reduced (P < 0.05) body weights and chest girths compared with control birds at DPV 14, 42, 63, and 84. The results indicate that vaccination with a live anticoccidial vaccine provides immunity against a challenge infection that is sufficient to prevent gross pathology. However, early growth of feed restricted pullets may be adversely affected.

广泛使用活的抗球虫疫苗进行疫苗接种，以控制肉鸡育种中的球虫病。但是，限制饲喂期间的疫苗接种可能会影响小母鸡的早期生长。用Cobb-500-FF肉鸡种鸡进行了两个实验，以评估活的抗球虫疫苗产生的免疫水平，并研究低剂量的针叶艾美球虫，艾美球虫和最大艾美球虫疫苗接种对仔猪早期生长的影响。小鸡在饲料限制期间。在第一个实验中，未接种疫苗和已接种疫苗的小鸡在接种后第28、35、42、49和56天（DPV）被分配到电池笼中，并受到100,000枚大肠杆菌的卵囊攻击。在第二个实验中，将总共280日龄的小鸡分为2组，分别接种3种艾美球虫的0或500个卵囊。 在第一个实验中的所有时间点，接种疫苗的人群的盲肠总病变评分和滴落泛得分均显着降低（P <0.05），这表明禽类已获得针对大肠杆菌的挑战。在第二个实验中，用低剂量的艾美叶球菌疫苗接种的家禽显示减少（P 与DPV 14、42、63和84的对照鸟相比，体重和胸围<0.05）。结果表明，用活的抗球虫疫苗进行疫苗接种可提供针对挑战性感染的免疫力，足以预防总​​体病理。但是，受饲料限制的母鸡的早期生长可能受到不利影响。