Lactobacillus species have been reported to reduce nitrogen-containing compounds in poultry manure and produce a safe environment for birds and humans. The effects of Lactobacillus species (Lactobacillus paracasei, Lactobacillus plantarum, and Lactobacillus rhamnosus) on production performance, nitrogenous compounds in manure, specific biological components in serum, and uric acid (UA) concentration in the liver were investigated in an eight-week-long study. Forty-eight white Leghorn hens (52- to 54-week-old) were randomly assigned to 2 treatments; standard drinking water was considered the control, and the treatment included the control and probiotics. Individual probiotics were combined to produce a total concentration of approximately 1.84 × 10⁷ cfu/mL and 6.13 × 10⁶ cfu/mL for each isolate. All layers received the same commercial feed for 8 wk. Nitrogenous compounds measured in manure included ammonia (NH₃), ammonium nitrogen (NH₄-N), total Kjeldahl nitrogen (TKN), and total nitrogen (TN). Blood serum was analyzed for NH₃, UA, total protein, albumin, and creatine kinase. Uric acid concentration was also measured in the liver. No significant effects were observed for body weight, feed intake, egg production, and feed conversion ratio. Ammonia emissions and concentration, NH₄-N, TKN, and TN concentration were unaffected; however, the interaction of treatment and week showed significant reduction in NH₄-H. Moreover, NH₃ concentration was lowered significantly in serum of hens fed with probiotics compared with that of the control. There was no significant effect on UA concentration in the liver. Overall, the results indicated that supplementation of Lactobacillus species could be useful in decreasing NH₃ concentration in serum and depositing it in manure where other postconsumption methods (alum and urease inhibitors) could be used to reduce it. Reducing NH₃ concentration in serum and in manure should result in more profit for industry in reference to health and productivity of laying hens and welfare of workers. As well, reduction of NH₃ concentration satisfies the poultry industry's goal of reducing NH₃ emission in the environment.

据报道，乳酸杆菌可减少家禽粪便中的含氮化合物，并为鸟类和人类提供安全的环境。的影响乳杆菌种（副干酪乳杆菌，植物乳杆菌，和鼠李糖乳杆菌生产性能，在粪便的含氮化合物，在血清特异性生物成分，和尿酸（）UA在一项为期八周的研究中研究了肝脏中的胆固醇浓度。48只白色的来克亨鸡（52-54周龄）被随机分配到2种处理方法中。标准饮用水被认为是对照，治疗包括对照和益生菌。组合每个单独的益生菌，总浓度分别为1.84×10 ⁷  cfu / mL和6.13×10 ⁶  cfu / mL。所有图层都接受了8周的相同商业广告。粪肥中测得的氮化合物包括氨（NH ₃），铵态氮（NH ₄ -N），凯氏定氮（TKN）和总氮（TN））。分析血清中的NH ₃，UA，总蛋白，白蛋白和肌酸激酶。还测量了肝脏中的尿酸浓度。体重，采食量，产蛋量和饲料转化率均未见明显影响。氨气排放和浓度，NH ₄ -N，TKN和TN浓度不受影响；然而，处理和周的相互作用表明NH ₄ -H显着降低。而且，与对照相比，用益生菌喂养的母鸡血清中的NH ₃浓度显着降低。对肝脏中UA浓度没有显着影响。总体而言，结果表明补充乳酸杆菌这些物种可能有助于降低血清中的NH ₃浓度并将其沉积在粪肥中，而其他消耗后方法（铝和脲酶抑制剂）也可以用来减少其含量。降低血清和粪肥中的NH ₃浓度，应从蛋鸡的健康和生产力以及工人的福利方面为行业带来更多的利润。同样，减少NH ₃浓度也可以满足家禽业减少环境中NH ₃排放的目标。