Abstract The present study explored the influence of the varying concentrations of a proton generator, glucono-δ-lactone (GDL), promoting a cross-linking of the matrix to the dose-response of a PVA-GTA-I radiochromic gel dosimeter. This gel dosimeter was composed of iodide and polyvinyl alcohol crosslinked with glutaraldehyde (GTA) and combined with additives of GDL and fructose. Six sets of gel samples with GDL concentrations ranging from 50 to 300 mM was irradiated with 1–10 Gy doses using 137Cs gamma-rays. Dose response and temporal stability of the absorbance in the gel dosimeter as a function of the GDL concentration were investigated. The dose-response data showed good linearities in the dose range of 0–10 Gy from all GDL concentrations measured 48 h post-irradiation. The sensitivity became higher with increasing GDL concentration, but smaller increments were observed at higher GDL concentrations and then completely saturated around 250 mM. The recorded sensitivities from the PVA-GTA-I gel dosimeters were 3–4 times higher than PVA-I and LCV micelle gel dosimeters. Temporal stability data showed a similar trend in GDL concentrations of 100–300 mM, where a sharp increase of absorbance was seen in the first 24 h and then small fluctuations were observed up to 168 h post-irradiation. Meanwhile, the samples with 50 mM of GDL showed a gradual increase in absorbance after 48 h post-irradiation. Higher GDL concentrations tended to increase the rate of auto-oxidation.

中文翻译：

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葡萄糖酸-δ-内酯浓度对PVA-GTA-I放射变色凝胶剂量计灵敏度和稳定性的影响

摘要 本研究探讨了不同浓度的质子发生器葡萄糖酸-δ-内酯 (GDL) 促进基质交联对 PVA-GTA-I 放射变色凝胶剂量计的剂量响应的影响。该凝胶剂量计由碘化物和聚乙烯醇与戊二醛 (GTA) 交联并结合 GDL 和果糖添加剂组成。GDL 浓度范围为 50 至 300 mM 的六组凝胶样品使用 137Cs 伽马射线以 1-10 Gy 剂量进行照射。研究了作为 GDL 浓度函数的凝胶剂量计中吸光度的剂量响应和时间稳定性。剂量反应数据显示，照射后 48 小时测量的所有 GDL 浓度在 0-10 Gy 的剂量范围内具有良好的线性。随着 GDL 浓度的增加，灵敏度变得更高，但在较高的 GDL 浓度下观察到较小的增量，然后在 250 mM 左右完全饱和。PVA-GTA-I 凝胶剂量计记录的灵敏度比 PVA-I 和 LCV 胶束凝胶剂量计高 3-4 倍。时间稳定性数据显示 GDL 浓度为 100-300 mM 的类似趋势，其中在前 24 小时内看到吸光度急剧增加，然后在照射后 168 小时内观察到小波动。同时，含有 50 mM GDL 的样品在辐照后 48 小时后吸光度逐渐增加。较高的 GDL 浓度往往会增加自动氧化的速度。PVA-GTA-I 凝胶剂量计记录的灵敏度比 PVA-I 和 LCV 胶束凝胶剂量计高 3-4 倍。时间稳定性数据显示 GDL 浓度为 100-300 mM 的类似趋势，其中在前 24 小时内看到吸光度急剧增加，然后在照射后 168 小时内观察到小波动。同时，含有 50 mM GDL 的样品在辐照后 48 小时后吸光度逐渐增加。较高的 GDL 浓度往往会增加自动氧化的速度。PVA-GTA-I 凝胶剂量计记录的灵敏度比 PVA-I 和 LCV 胶束凝胶剂量计高 3-4 倍。时间稳定性数据显示 GDL 浓度为 100-300 mM 的类似趋势，其中在前 24 小时内看到吸光度急剧增加，然后在照射后 168 小时内观察到小波动。同时，含有 50 mM GDL 的样品在辐照后 48 小时后吸光度逐渐增加。较高的 GDL 浓度往往会增加自动氧化的速度。含有 50 mM GDL 的样品在辐照后 48 小时后吸光度逐渐增加。较高的 GDL 浓度往往会增加自动氧化的速度。含有 50 mM GDL 的样品在辐照后 48 小时后吸光度逐渐增加。较高的 GDL 浓度往往会增加自动氧化的速度。