Tissue spheroids (TS) represent a building block in biofabrication. In this study, authors suggest a procedure for systematic multiparametric characterization of TS to generate viable cell aggregates with defined morphology, biomechanical properties and uniform predictable geometry from different types of cells. The cover image represents this process as an automated production line equipped with different tools. This is reported by Elizaveta V. Koudan, Anna A. Gryadunova, Pavel A. Karalkin, Janetta V. Korneva, Nina Y. Meteleva, Igor I. Babichenko, Aleksey V. Volkov, Sergey A. Rodionov, Vladislav A. Parfenov, Frederico D. A. S. Pereira, Yusef D. Khesuani, Vladimir A. Mironov, Elena A. Bulanova in article 1900217.

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封面正面：《生物技术杂志》 5/2020

组织球体（TS）代表生物制造的基本要素。在这项研究中，作者建议对TS进行系统多参数表征的程序，以从不同类型的细胞生成具有确定的形态，生物力学特性和一致的可预测几何形状的可行细胞聚集体。封面图像将此过程表示为配备了不同工具的自动化生产线。Elizaveta V. Koudan，Anna A. Gryadunova，Pavel A. Karalkin，Janetta V. Korneva，Nina Y. Meteleva，Igor I. Babichenko，Aleksey V.Volkov，Sergey A. Rodionov，Vladislav A. Parfenov，Frederico对此进行了报道。 DAS Pereira，Yusef D.Khesuani，Vladimir A.Mironov，Elena A.Bulanova在第1900217条中。