We report the synthesis and characterization of crystalline calcium phosphate (CaP) nanostructures from calcium inositol hexakisphosphate (CaIP 6 ) precursor in water-ethanol mixed solutions. We show how these CaPs can be prepared by a solvo-hydrothermal reaction and determined their compositions and structures using a battery of material characterization techniques. Our results show that only the hydroxyapatite (HAP) and dicalcium phosphate anhydrous (DCPA) phases of CaP were present in the nanostructures produced in water-ethanol mixtures, and that HAP/DCPA ratio of the rod- and plate-shaped CaP nanostructures produced were affected by the amount of ethanol present in these mixtures. The described method can be used to improve morphological control of CaP-based biomate-rials and has potential use in bone regenerative medicine.

中文翻译：

---

六磷酸肌醇钙前体在水-乙醇混合溶液中溶剂水热合成磷酸钙纳米结构

我们报告了水-乙醇混合溶液中肌醇六磷酸钙 (CaIP 6 ) 前体的结晶磷酸钙 (CaP) 纳米结构的合成和表征。我们展示了如何通过溶剂水热反应制备这些 CaP，并使用一系列材料表征技术确定它们的组成和结构。我们的结果表明，在水-乙醇混合物中产生的纳米结构中仅存在 CaP 的羟基磷灰石 (HAP) 和无水磷酸二钙 (DCPA) 相，并且所产生的棒状和板状 CaP 纳米结构的 HAP/DCPA 比率为受这些混合物中乙醇含量的影响。所描述的方法可用于改善基于 CaP 的生物材料的形态控制, 并在骨再生医学中具有潜在用途。