Stretchable, self-healing and tissue-adhesive zwitterionic hydrogels as strain sensors for wireless monitoring of organ motions,Materials Horizons

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Stretchable, self-healing and tissue-adhesive zwitterionic hydrogels as strain sensors for wireless monitoring of organ motions
Materials Horizons ( IF 12.2 ) Pub Date : 2020-04-29 , DOI: 10.1039/d0mh00361a
Xinjie Pei _{1,

2,

3,

4,

5} , Hua Zhang _{4,

5,

6,

7,

8} , Yang Zhou _{4,

5,

6,

7,

8} , Linjie Zhou _{1,

2,

3,

4} , Jun Fu _{1,

2,

3,

4}

Affiliation

Skin-inspired sensors have great potential applications in wearable and implantable devices to monitor human motions. Robust tissue adhesion, fatigue resistance, and biocompatibility are desired for in situ signal capture and wireless transmission. Inspired by the mussel and zwitterionic adhesion mechanisms, we prepared novel stretchable, self-healing and polydopamine zwitterionic nanocomposite hydrogels that provide reversible and robust adhesion to tissues with a strength up to 19.4 kPa and a strain sensitivity of 4.3. The hydrogel sensors robustly adhere to organs like the heart, liver, and lungs to capture signals for remote monitoring and diagnostics through wireless transmission.

中文翻译：

可拉伸，自我修复和组织粘附性两性离子水凝胶，作为应变传感器，用于无线监测器官运动

受皮肤启发的传感器在可穿戴和可植入设备中用于监视人体运动具有巨大的潜在应用。对于原位信号捕获和无线传输，需要强大的组织粘附力，抗疲劳性和生物相容性。受贻贝和两性离子粘附机制的启发，我们制备了新型可拉伸，自修复和聚多巴胺两性离子纳米复合水凝胶，可对组织提供可逆且牢固的粘附力，强度高达19.4 kPa，应变敏感性为4.3。水凝胶传感器牢固地粘附在心脏，肝脏和肺等器官上，以捕获信号，从而通过无线传输进行远程监控和诊断。

更新日期：2020-07-06

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