Hydropersulfides are reported to be good biological reductants, superior to thiols and akin to selenols. As such, they have been previously shown to reduce metalloproteins such as ferric myoglobin and ferric cytochrome c to their ferrous forms under conditions where little or no reduction from corresponding thiols is observed. Not surprisingly, the reduction of ferric myoglobin to ferrous myoglobin under aerobic conditions results in the generation of oxymyoglobin (dioxygen bound ferrous myoglobin). Previous studies have demonstrated that oxymyoglobin can also act as an oxidant with highly reducing species such as hydroxylamine and ascorbate. Considering the reducing properties of hydropersulfides, it is possible that they can also react with oxymyoglobin similarly to hydroxylamine or ascorbate. Herein, this reaction is examined and indeed hydropersulfides are found to react with oxymyoglobin similarly to other reducing species leading to a fleeting ferric myoglobin which is rapidly reduced to the ferrous form also by hydropersulfide.

中文翻译：

---

氢过硫化物（RSSH）与肌红蛋白的反应。

据报道，氢过硫化物是良好的生物还原剂，优于硫醇，类似于硒醇。这样，先前已显示它们在观察到很少或没有从相应硫醇还原的条件下将金属蛋白如铁肌红蛋白和细胞色素c还原为亚铁形式。不足为奇的是，在有氧条件下，铁肌红蛋白还原为亚铁肌红蛋白会导致产生氧肌红蛋白（与氧结合的亚铁肌红蛋白）。先前的研究表明，氧肌红蛋白还可以与具有高度还原性的物质（例如羟胺和抗坏血酸盐）一起用作氧化剂。考虑到氢过硫化物的还原性质，它们也可以类似于羟胺或抗坏血酸与氧代肌红蛋白反应。在这里