Gibberellin (GA) hormones regulate the development of plants and their responses to environmental signals. The final part of GA biosynthesis is catalyzed by multifunctional 2-oxoglutarate-dependent dioxygenases, which are encoded by multigene families. According to their enzymatic properties and physiological functions, GA-oxidases are classified as anabolic or catabolic enzymes. Together they allow complex regulation of the GA biosynthetic pathway, which adapts the specific hormonal needs of a plant during development and interaction with its environment. In this review, we combine recent advances in enzymatic characterization of the multifunctional GA-oxidases, in particular, from cucumber and Arabidopsis that have been most comprehensively investigated.

中文翻译：

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赤霉素合成的多功能双加氧酶。

赤霉素（GA）激素调节植物的生长及其对环境信号的响应。GA生物合成的最后部分由多功能2-氧代戊二酸酯依赖性双加氧酶催化，该酶由多基因家族编码。根据GA-氧化酶的酶学性质和生理功能，将其分类为同化或分解代谢酶。它们共同作用，可以对GA生物合成途径进行复杂的调节，从而适应植物在发育过程中及其与环境的相互作用中特定的激素需求。在这篇综述中，我们结合了多功能GA氧化酶的酶学表征的最新进展，特别是对黄瓜和拟南芥进行了最全面的研究。