Panel-based targeted exome sequencing reveals novel candidate susceptibility loci for age-related cataracts in Chinese Cohort.,Molecular Genetics & Genomic Medicine

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Panel-based targeted exome sequencing reveals novel candidate susceptibility loci for age-related cataracts in Chinese Cohort.
Molecular Genetics & Genomic Medicine ( IF 1.5 ) Pub Date : 2020-04-26 , DOI: 10.1002/mgg3.1218
Jian-Kang Li _{1,

2,

3} , Li-Li Li ₄ , Wei Li _{2,

3,

5} , Zi-Wei Wang _{2,

5} , Feng-Juan Gao _{6,

7,

8} , Fang-Yuan Hu _{6,

7,

8} , Sheng-Hai Zhang _{6,

7,

8} , Shou-Fang Qu ₄ , Jie Huang ₄ , Lu-Sheng Wang _{1,

2} , Ji-Hong Wu _{6,

7,

8} , Fang Chen _{2,

3}

Affiliation

Age‐related cataracts (ARC) is the most common blinding eye disease worldwide, and its incidence tend to become younger. However, the relationship between genetic factors and mechanisms is not fully understood. The aim of the study was to further clarify the relationship between ARC and genetic mechanisms in East Asian populations and to elucidate the pathogenesis.

更新日期：2020-04-26

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