Biotechnology offers a green alternative for the production of fuels and chemicals using microbes. Although traditional model hosts such as Escherichia coli and Saccharomyces cerevisiae have been widely studied and used, they may not be the best hosts for industrial application. In this review, we explore recent advances in the use of nonconventional hosts for the production of a variety of fuel, cosmetics, perfumes, food, and pharmaceuticals. Specifically, we highlight twenty-seven popular molecules with a special focus on recent progress and metabolic engineering strategies to enable improved production of fuels and chemicals. These examples demonstrate the promise of nonconventional host engineering.

中文翻译：

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用于生产燃料和化学品的非常规宿主。

生物技术为使用微生物生产燃料和化学品提供了一种绿色替代方案。尽管大肠杆菌和酿酒酵母等传统模式宿主已被广泛研究和使用，但它们可能不是工业应用的最佳宿主。在这篇综述中，我们探讨了使用非常规宿主生产各种燃料、化妆品、香水、食品和药品的最新进展。具体来说，我们重点介绍了 27 种流行的分子，特别关注最近的进展和代谢工程策略，以改善燃料和化学品的生产。这些例子证明了非常规宿主工程的前景。