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Synthesis of Pyrido[2,3‐b]indoles via Brønsted‐Acid‐Promoted Decarboxylative Annulation of 3‐Bromopropenals and Ethyl 2‐Amino‐1H‐indole‐3‐carboxylates
Asian Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-04-26 , DOI: 10.1002/ajoc.202000175 Tang‐Hao Yang, Veerababurao Kavala, Chun‐Wei Kuo, Ching‐Fa Yao
Asian Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-04-26 , DOI: 10.1002/ajoc.202000175 Tang‐Hao Yang, Veerababurao Kavala, Chun‐Wei Kuo, Ching‐Fa Yao
The present methodology describes a versatile pathway to furnish α‐carbolines from relatively stable 2‐amino indole derivatives and 3‐bromopropenal. High substrate tolerance, nonmetallic, more efficient, and mild reaction conditions are important aspects.
中文翻译:
通过布朗斯台德酸促进的3-溴丙烯醛和2-氨基-1H-1吲哚-3-羧酸乙酯的脱羧环化反应合成吡啶并[2,3-b]吲哚
本方法学描述了从相对稳定的2-氨基吲哚衍生物和3-溴丙烯醛制备α-咔啉的通用途径。高基材耐受性,非金属,更有效和温和的反应条件是重要的方面。
更新日期:2020-04-26
中文翻译:
通过布朗斯台德酸促进的3-溴丙烯醛和2-氨基-1H-1吲哚-3-羧酸乙酯的脱羧环化反应合成吡啶并[2,3-b]吲哚
本方法学描述了从相对稳定的2-氨基吲哚衍生物和3-溴丙烯醛制备α-咔啉的通用途径。高基材耐受性,非金属,更有效和温和的反应条件是重要的方面。