Background: The number of patients suffering from coronary heart disease with cancer is rising. There is scarce evidence concerning the biomarkers related to prognosis among patients undergoing percutaneous coronary intervention (PCI) with cancer. Thus, the aim of this study was to investigate the association between red blood cell distribution width (RDW) and prognosis in this population.Methods: A total of 172 patients undergoing PCI with previous history of cancer were enrolled in this retrospective study. The endpoint was long-term all-cause mortality. According to tertiles of RDW, the patients were classified into three groups: Tertile 1 (RDW <12.8%), Tertile 2 (RDW ≥12.8% and <13.5%) and Tertile 3 (RDW ≥13.5%).Results: During an average follow-up period of 33.3 months, 29 deaths occurred. Compared with Tertile 3, mortality of Tertile 1 and Tertile 2 was significantly lower in the Kaplan-Meier analysis. In multivariate Cox regression analysis, RDW remained an independent risk factor of mortality (HR: 1.938, 95% CI: 1.295-2.655, p < 0.001). The all-cause mortality in Tertile 3 was significantly higher than that in Tertile 1 (HR: 5.766; 95% CI: 1.426-23.310, p = 0.014).Conclusions: An elevated RDW level (≥13.5%) was associated with long-term all-cause mortality among patients undergoing PCI with previous history of cancer.

中文翻译：

---

经皮冠状动脉介入治疗与先前癌症史的患者之间的红细胞分布宽度与长期死亡率之间的关联。

背景：患有冠心病并患有癌症的患者人数正在上升。在接受癌症经皮冠状动脉介入治疗（PCI）的患者中，很少有证据涉及与预后相关的生物标志物。因此，本研究的目的是调查该人群中红细胞分布宽度（RDW）与预后之间的关系。方法：本研究共纳入172位接受过PCI且有癌史的患者。终点是长期全因死亡率。根据RDW的三分位数，将患者分为三组：第一分位数（RDW <12.8％），第二分位数2（RDW≥12.8％和<13.5％）和第三分位数3（RDW≥13.5％）。随访期33.3个月，发生29例死亡。与Tertile 3相比，在Kaplan-Meier分析中，Tertile 1和Tertile 2的死亡率显着降低。在多因素Cox回归分析中，RDW仍然是死亡率的独立危险因素（HR：1.938，95％CI：1.295-2.655，p <0.001）。三分位数3的全因死亡率显着高于三分位数1（HR：5.766; 95％CI：1.426-23.310，p = 0.014）。结论：RDW水平升高（≥13.5％）与长期服用RW有关。接受过既往癌症史的PCI患者的全因死亡率。