A molecularly-imprinted polymer decorated on graphene oxide (GO/MIP) was designed with the aid of molecular modeling to select an appropriate functional monomer and to optimize its ratio to an imprinting molecule of quercetin (Qu) for the selective adsorption of Qu. The GO/MIP was prepared by free radical polymerization on the surface of GO using a functional monomer of 4-vinylpyridine at its optimal molar ratio to Qu of 4:1. The GO/MIP was characterized by Fourier transform infrared spectroscopy, elemental analysis, Raman spectroscopy, thermogravimetric analysis, scanning electron microscopy, atomic force microscopy and adsorption measurements. Results indicate that the equilibrium time and adsorption capacity of the GO/MIP towards Qu are 30 min and 30.61 mg g⁻¹ at 298 K, respectively and the adsorption data are well described by a pseudo-second-order kinetic model and the Langmuir isotherm model. From competing adsorption tests in a solution containing three flavonoids (Qu, kaempferol and rutin), the GO/MIP displays an excellent recognition ability for Qu with faster adsorption kinetics than bulk MIP without GO, and has the highest adsorption capacity and selectivity for Qu among the three flavonoids, which is superior to the un-imprinted polymer.

借助分子建模设计了装饰在氧化石墨烯上的分子印迹聚合物（GO / MIP），以选择合适的功能单体，并优化其与槲皮素（Qu）印迹分子的比例，以选择性吸附Qu。通过使用4-乙烯基吡啶的官能单体以其与Qu的最佳摩尔比为4的4-乙烯基吡啶的官能单体在GO表面上进行自由基聚合来制备GO / MIP。GO / MIP的特征在于傅立叶变换红外光谱，元素分析，拉曼光谱，热重分析，扫描电子显微镜，原子力显微镜和吸附测量。结果表明，GO / MIP对Qu的平衡时间和吸附能力分别为30 min和30.61 mg g ^-1在298 K的温度下，吸附数据可以通过拟二阶动力学模型和Langmuir等温线模型很好地描述。通过在包含三种类黄酮（Qu，山奈酚和芦丁）的溶液中进行的竞争性吸附测试，GO / MIP对Qu的识别能力极强，比没有GO的本体MIP的吸附动力学更快，并且具有最高的吸附能力和对Qu的选择性三种类黄酮，优于未印迹的聚合物。