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Anything but Conventional Chromatography Approaches in Bioseparation.
Biotechnology Journal ( IF 3.2 ) Pub Date : 2020-04-25 , DOI: 10.1002/biot.201900274 Ana Cecília Afonso Roque 1 , Ana Sofia Pina 1 , Ana Margarida Azevedo 2 , Raquel Aires-Barros 2 , Alois Jungbauer 3 , Gianluca Di Profio 4 , Jerry Y Y Heng 5 , Jonathan Haigh 6 , Marcel Ottens 7
Biotechnology Journal ( IF 3.2 ) Pub Date : 2020-04-25 , DOI: 10.1002/biot.201900274 Ana Cecília Afonso Roque 1 , Ana Sofia Pina 1 , Ana Margarida Azevedo 2 , Raquel Aires-Barros 2 , Alois Jungbauer 3 , Gianluca Di Profio 4 , Jerry Y Y Heng 5 , Jonathan Haigh 6 , Marcel Ottens 7
Affiliation
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While packed bed chromatography, known as conventional chromatography, has been serving the biopharmaceutical industry for decades as the bioseparation method of choice, alternative approaches are likely to take an increasing leading role in the next few years. The high number of new biological drugs under development, and the need to make biopharmaceuticals widely accessible, has been driving the academia and industry in the quest of anything but conventional chromatography approaches. In this perspective paper, these alternative approaches are discussed in view of current and future challenges in the downstream processing field.
中文翻译：
生物分离中除常规色谱方法外的任何方法。
尽管填充床色谱法（称为常规色谱法）作为选择的生物分离方法已经为生物制药行业服务了数十年，但替代方法可能在未来几年中扮演越来越重要的角色。大量新的生物药物正在开发中，以及广泛使用生物制药的需求，驱使学术界和工业界寻求除常规色谱方法以外的任何方法。在此透视图中，鉴于下游加工领域当前和未来的挑战，讨论了这些替代方法。
更新日期：2020-04-25
中文翻译：
生物分离中除常规色谱方法外的任何方法。
尽管填充床色谱法（称为常规色谱法）作为选择的生物分离方法已经为生物制药行业服务了数十年，但替代方法可能在未来几年中扮演越来越重要的角色。大量新的生物药物正在开发中，以及广泛使用生物制药的需求，驱使学术界和工业界寻求除常规色谱方法以外的任何方法。在此透视图中，鉴于下游加工领域当前和未来的挑战，讨论了这些替代方法。
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