Endocytosis is critical for many functions in eukaryotic cells. Uptake of host cell cytosol, an indispensable endocytic process in malaria blood-stage parasites, has been known for a long time. However, it is only recently that the proteins involved in this process have started to emerge. Unexpectedly, some of these proteins revealed a critical role for endocytosis in artemisinin resistance. More recently, endocytosis was discovered in both intracellular and extracellular Toxoplasma gondii parasites. Here, we review these findings, compare the endolysosomal systems of Toxoplasma and Plasmodium parasites, and present current knowledge about endocytic mechanisms in apicomplexans.

中文翻译：

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疟原虫和弓形虫寄生虫的内吞作用。

内吞作用对真核细胞的许多功能至关重要。宿主细胞胞质溶胶的吸收是疟疾血液阶段寄生虫不可或缺的内吞过程，长期以来一直为人所知。然而，直到最近，参与这一过程的蛋白质才开始出现。出乎意料的是，这些蛋白质中的一些揭示了内吞作用在青蒿素抗性中的关键作用。最近，在细胞内和细胞外弓形虫寄生虫中都发现了内吞作用。在这里，我们回顾了这些发现，比较了弓形虫和疟原虫寄生虫的内溶酶体系统，并介绍了有关顶复体内吞机制的最新知识。